Clinicopathological features and treatment outcomes of patients with fibrolamellar hepatocellular carcinoma: a retrospective multicenter study

Clinicopathological features and treatment outcomes of patients with fibrolamellar hepatocellular carcinoma: a retrospective multicenter study

BACKGROUND: Fibrolamellar Hepatocellular Carcinoma (FLHCC) is a rare primary liver tumour that is distinct from conventional HCC in both histopathological and clinical features. There is no clear consensus on its treatment. OBJECTIVE: Assess the demographics, prognosis, and treatment— particularly s...

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Main Authors: Ali Kaan Güren, Hilal Polat, Eyüp Çoban, Emir Çerme, Gizem Bakır Kahveci, Aslı Geçgel, Pınar Ezgi Dama, Lamia Şeker Can, Sedat Biter, Sıla Soylu, Nargiz Majidova, Nadiye Sever, Erkam Kocaaslan, Pınar Erel, Yeşim Ağyol, Abdussamet Çelebi, Rukiye Arıkan, Selver Işık, İlkay Tuğba Ünek, Ertuğrul Bayram, Ozan Yazıcı, Adem Deligönül, Zeynep Hande Turna, Murat Araz, İbrahim Vedat Bayoğlu, Osman Köstek, Murat Sarı
Format: Article
Language:English
Published: King Faisal Specialist Hospital and Research Centre 2025-07-01
Series:Annals of Saudi Medicine
Subjects:
Fibrolamellar HCC
Gemcitabine-oxaliplatin
Sorafenib
Immunotherapy
DNAJB1-PRKACA
Online Access:http://www.annsaudimed.net/doi/10.5144/0256-4947.2025.249
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