Clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestations
Objective To analyze the clinical and histopathological features of skin manifestations of inflammatory bowel disease (IBD) in order to provide guidance for clinical diagnosis. Methods Clinical and pathological characteristics of 2 patients with IBD were retrospectively analyzed. Results One patient...
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editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2024-08-01
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| Series: | Pifu-xingbing zhenliaoxue zazhi |
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| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.08.002 |
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| author | QIU Xiaoying XIA Chuangang XIAO Wen CHEN Fangru |
| author_facet | QIU Xiaoying XIA Chuangang XIAO Wen CHEN Fangru |
| author_sort | QIU Xiaoying |
| collection | DOAJ |
| description | Objective To analyze the clinical and histopathological features of skin manifestations of inflammatory bowel disease (IBD) in order to provide guidance for clinical diagnosis. Methods Clinical and pathological characteristics of 2 patients with IBD were retrospectively analyzed. Results One patient had Crohn's disease manifested by perianal erythema and ulcers, and histopathology showed non-caseous and non-infectious granuloma in the dermis. Treatment with Ustekinumab decreased the ulcerative area. In another case of ulcerative colitis with extraintestinal manifestations, erythemas and nodules were all over the body, and ulcers were on the lower legs and buttocks. Histopathology showed dermal neutrophil infiltration. The skin lesions partially subsided after the treatment with Infliximab. Conclusions IBD with cutaneous manifestations has different histopathological characteristics, and clinicians should make the diagnosis based on both clinical manifestations and histopathological features in order to avoid misdiagnosis and missed diagnosis. |
| format | Article |
| id | doaj-art-dc813b9fa94b439593e3711dada1cbec |
| institution | OA Journals |
| issn | 1674-8468 |
| language | zho |
| publishDate | 2024-08-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj-art-dc813b9fa94b439593e3711dada1cbec2025-08-20T02:12:24Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682024-08-0131851852310.3969/j.issn.1674-8468.2024.08.002Clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestationsQIU Xiaoying0XIA Chuangang1XIAO Wen2CHEN Fangru3Affiliated Hospital of Guilin Medical College, Guilin 541001, China;Liuzhou Workers' Hospital, Liuzhou 545005, ChinaLiuzhou Workers' Hospital, Liuzhou 545005, ChinaAffiliated Hospital of Guilin Medical College, Guilin 541001, China;Objective To analyze the clinical and histopathological features of skin manifestations of inflammatory bowel disease (IBD) in order to provide guidance for clinical diagnosis. Methods Clinical and pathological characteristics of 2 patients with IBD were retrospectively analyzed. Results One patient had Crohn's disease manifested by perianal erythema and ulcers, and histopathology showed non-caseous and non-infectious granuloma in the dermis. Treatment with Ustekinumab decreased the ulcerative area. In another case of ulcerative colitis with extraintestinal manifestations, erythemas and nodules were all over the body, and ulcers were on the lower legs and buttocks. Histopathology showed dermal neutrophil infiltration. The skin lesions partially subsided after the treatment with Infliximab. Conclusions IBD with cutaneous manifestations has different histopathological characteristics, and clinicians should make the diagnosis based on both clinical manifestations and histopathological features in order to avoid misdiagnosis and missed diagnosis.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.08.002inflammatory bowel diseasecrohn's diseaseulcerative colitisskin manifestationspathological features |
| spellingShingle | QIU Xiaoying XIA Chuangang XIAO Wen CHEN Fangru Clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestations Pifu-xingbing zhenliaoxue zazhi inflammatory bowel disease crohn's disease ulcerative colitis skin manifestations pathological features |
| title | Clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestations |
| title_full | Clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestations |
| title_fullStr | Clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestations |
| title_full_unstemmed | Clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestations |
| title_short | Clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestations |
| title_sort | clinical and pathological analyses of two cases of inflammatory bowel disease with cutaneous manifestations |
| topic | inflammatory bowel disease crohn's disease ulcerative colitis skin manifestations pathological features |
| url | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.08.002 |
| work_keys_str_mv | AT qiuxiaoying clinicalandpathologicalanalysesoftwocasesofinflammatoryboweldiseasewithcutaneousmanifestations AT xiachuangang clinicalandpathologicalanalysesoftwocasesofinflammatoryboweldiseasewithcutaneousmanifestations AT xiaowen clinicalandpathologicalanalysesoftwocasesofinflammatoryboweldiseasewithcutaneousmanifestations AT chenfangru clinicalandpathologicalanalysesoftwocasesofinflammatoryboweldiseasewithcutaneousmanifestations |