Pigmented Tumour of the Eyelid with Unexpected Findings

A 63-year-old patient presented with a small painless nodular tumour of his left lower eyelid which had increased in size over the last few weeks. The tumour was excised by wedge resection and submitted for ophthalmopathologic examination. Histopathologic examination revealed a cystic lesion of apo...

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Main Authors: Anne C. Hunold, Martina C. Herwig, Frank G. Holz, Hans-Peter Fischer, Karin U. Loeffler
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2012/471368
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author Anne C. Hunold
Martina C. Herwig
Frank G. Holz
Hans-Peter Fischer
Karin U. Loeffler
author_facet Anne C. Hunold
Martina C. Herwig
Frank G. Holz
Hans-Peter Fischer
Karin U. Loeffler
author_sort Anne C. Hunold
collection DOAJ
description A 63-year-old patient presented with a small painless nodular tumour of his left lower eyelid which had increased in size over the last few weeks. The tumour was excised by wedge resection and submitted for ophthalmopathologic examination. Histopathologic examination revealed a cystic lesion of apocrine origin with focal proliferations. The proliferative cells appeared pleomorphic and displayed marked atypia. Staining with Ki67 revealed a significant mitotic activity supporting the diagnosis of an apocrine adenocarcinoma of Moll. As the lesion displayed in most parts characteristics of a benign apocrine hidrocystoma, a thorough and critical histopathological examination is required in such cases to avoid missing an early malignant transformation.
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publishDate 2012-01-01
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series Case Reports in Pathology
spelling doaj-art-dc79a609ecaf4ee7a9973ca3296a7af32025-08-20T02:21:38ZengWileyCase Reports in Pathology2090-67812090-679X2012-01-01201210.1155/2012/471368471368Pigmented Tumour of the Eyelid with Unexpected FindingsAnne C. Hunold0Martina C. Herwig1Frank G. Holz2Hans-Peter Fischer3Karin U. Loeffler4Department of Ophthalmology, Marienhospital Aachen, Friedrich-Ebert-Allee 98, 52066 Aachen, GermanyDepartment of Ophthalmology, University of Bonn, Ernst-Abbe-Straße 2, 53127 Bonn, GermanyDepartment of Ophthalmology, University of Bonn, Ernst-Abbe-Straße 2, 53127 Bonn, GermanyDepartment of Pathology, University of Bonn, Sigmund-Freud-Straße 25, 53127 Bonn, GermanyDepartment of Ophthalmology, University of Bonn, Ernst-Abbe-Straße 2, 53127 Bonn, GermanyA 63-year-old patient presented with a small painless nodular tumour of his left lower eyelid which had increased in size over the last few weeks. The tumour was excised by wedge resection and submitted for ophthalmopathologic examination. Histopathologic examination revealed a cystic lesion of apocrine origin with focal proliferations. The proliferative cells appeared pleomorphic and displayed marked atypia. Staining with Ki67 revealed a significant mitotic activity supporting the diagnosis of an apocrine adenocarcinoma of Moll. As the lesion displayed in most parts characteristics of a benign apocrine hidrocystoma, a thorough and critical histopathological examination is required in such cases to avoid missing an early malignant transformation.http://dx.doi.org/10.1155/2012/471368
spellingShingle Anne C. Hunold
Martina C. Herwig
Frank G. Holz
Hans-Peter Fischer
Karin U. Loeffler
Pigmented Tumour of the Eyelid with Unexpected Findings
Case Reports in Pathology
title Pigmented Tumour of the Eyelid with Unexpected Findings
title_full Pigmented Tumour of the Eyelid with Unexpected Findings
title_fullStr Pigmented Tumour of the Eyelid with Unexpected Findings
title_full_unstemmed Pigmented Tumour of the Eyelid with Unexpected Findings
title_short Pigmented Tumour of the Eyelid with Unexpected Findings
title_sort pigmented tumour of the eyelid with unexpected findings
url http://dx.doi.org/10.1155/2012/471368
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AT hanspeterfischer pigmentedtumouroftheeyelidwithunexpectedfindings
AT karinuloeffler pigmentedtumouroftheeyelidwithunexpectedfindings