Virally mediated expression of a biologically active peptide to restrain the nuclear functions of ERK1/2 attenuates learning extinction but not acquisition
Abstract Peptide drug technologies offer powerful approaches to develop potent and selective lead molecules for therapeutic and research applications. However, new and optimized delivery approaches are necessary to overcome current pitfalls including fast degradation in cells and tissue. Extracellul...
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| Main Authors: | Bar Izkovich, Adonis Yiannakas, Sapir Ne’eman, Sailendrakumar Kolatt Chandran, Kobi Rosenblum, Efrat Edry |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
|
| Series: | Molecular Brain |
| Online Access: | https://doi.org/10.1186/s13041-025-01190-1 |
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