Identification of robust and abundant reference transcripts for EV mRNA cargo normalization

Identification of robust and abundant reference transcripts for EV mRNA cargo normalization

Extracellular vesicles (EVs) have been investigated intensively because of their potential as biomarkers of disease and their versatility as bioengineered therapeutic nanoparticles. EVs carry diverse biomolecular cargo, but absolute quantification has been challenging due to a lack of established mo...

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Bibliographic Details
Main Authors: Antje M. Zickler, Radosław Grochowski, André Görgens, Erik Bäcklin, Maximilian Kordes, J.-Matthias Löhr, Joel Z. Nordin, Samir EL Andaloussi, Daniel W. Hagey
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Extracellular Vesicle
Subjects:
Extracellular vesicles
mRNA
Transcript
Standards
Normalization
RNA-Sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2773041725000010
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