Human cytomegalovirus induces neuronal gene expression through IE1 for viral maturation

Abstract Viral invasion of the host cell causes some of the most dramatic changes in biology. Human cytomegalovirus (HCMV) extensively remodels host cells, altering nuclear shape and generating a cytoplasmic viral-induced assembly compartment (vIAC). How these striking morphology changes occur in th...

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Bibliographic Details
Main Authors: Laurel E. Kelnhofer-Millevolte, Julian R. Smith, Daniel H. Nguyen, Lea S. Wilson, Hannah C. Lewis, Edward A. Arnold, Mia R. Brinkley, Kihye Shin, Jin-Hyun Ahn, Eui Tae Kim, Katarzyna Kulej, Adam P. Geballe, Srinivas Ramachandran, Daphne C. Avgousti
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61915-7
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