Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamomum camphora Leaves against Lasioderma serricorne

During our screening program for agrochemicals from Chinese medicinal herbs and wild plants, the essential oil of Cinnamomum camphora leaves was found to possess strong fumigant and contact toxicity against Lasioderma serricorne adults with LC50/LD50 values of 2.5 mg/L air and 21.25 μg/adult, respec...

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Main Authors: Hai Ping Chen, Kai Yang, Chun Xue You, Ning Lei, Rui Qi Sun, Zhu Feng Geng, Ping Ma, Qian Cai, Shu Shan Du, Zhi Wei Deng
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2014/963729
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author Hai Ping Chen
Kai Yang
Chun Xue You
Ning Lei
Rui Qi Sun
Zhu Feng Geng
Ping Ma
Qian Cai
Shu Shan Du
Zhi Wei Deng
author_facet Hai Ping Chen
Kai Yang
Chun Xue You
Ning Lei
Rui Qi Sun
Zhu Feng Geng
Ping Ma
Qian Cai
Shu Shan Du
Zhi Wei Deng
author_sort Hai Ping Chen
collection DOAJ
description During our screening program for agrochemicals from Chinese medicinal herbs and wild plants, the essential oil of Cinnamomum camphora leaves was found to possess strong fumigant and contact toxicity against Lasioderma serricorne adults with LC50/LD50 values of 2.5 mg/L air and 21.25 μg/adult, respectively. The essential oil obtained by hydrodistillation was investigated by GC and GC-MS. The main components of the essential oil were identified to be D-camphor (40.54%), linalool (22.92%), cineole (11.26%), and 3,7,11-trimethyl-3-hydroxy-6,10-dodecadien-1-yl acetate (4.50%). Bioactivity-directed chromatographic separation on repeated silica gel columns led to the isolation of D-camphor and linalool. D-camphor and linalool showed strong fumigant toxicity (LC50 = 2.36 and 18.04 mg/L air, resp.) and contact toxicity (LD50 = 13.44 and 12.74 μg/adult, resp.) against L. serricorne. The results indicate that the essential oil of C. camphora and its active compounds had the potential to be developed as natural fumigants and insecticides for control of L. serricorne.
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spelling doaj-art-dc6554b3920b47069c1966c3fae88f182025-08-20T03:23:56ZengWileyJournal of Chemistry2090-90632090-90712014-01-01201410.1155/2014/963729963729Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamomum camphora Leaves against Lasioderma serricorneHai Ping Chen0Kai Yang1Chun Xue You2Ning Lei3Rui Qi Sun4Zhu Feng Geng5Ping Ma6Qian Cai7Shu Shan Du8Zhi Wei Deng9Protection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory, Beijing Normal University, Haidian District, Beijing 100875, ChinaProtection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory, Beijing Normal University, Haidian District, Beijing 100875, ChinaProtection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory, Beijing Normal University, Haidian District, Beijing 100875, ChinaDepartment of Pharmacy, General Hospital of Second Artillery, PLA, Haidian District, Beijing 100088, ChinaAnalytical and Testing Center, Beijing Normal University, Beijing 100875, ChinaAnalytical and Testing Center, Beijing Normal University, Beijing 100875, ChinaDepartment of Pharmacy, General Hospital of Second Artillery, PLA, Haidian District, Beijing 100088, ChinaCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning 116600, ChinaProtection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory, Beijing Normal University, Haidian District, Beijing 100875, ChinaAnalytical and Testing Center, Beijing Normal University, Beijing 100875, ChinaDuring our screening program for agrochemicals from Chinese medicinal herbs and wild plants, the essential oil of Cinnamomum camphora leaves was found to possess strong fumigant and contact toxicity against Lasioderma serricorne adults with LC50/LD50 values of 2.5 mg/L air and 21.25 μg/adult, respectively. The essential oil obtained by hydrodistillation was investigated by GC and GC-MS. The main components of the essential oil were identified to be D-camphor (40.54%), linalool (22.92%), cineole (11.26%), and 3,7,11-trimethyl-3-hydroxy-6,10-dodecadien-1-yl acetate (4.50%). Bioactivity-directed chromatographic separation on repeated silica gel columns led to the isolation of D-camphor and linalool. D-camphor and linalool showed strong fumigant toxicity (LC50 = 2.36 and 18.04 mg/L air, resp.) and contact toxicity (LD50 = 13.44 and 12.74 μg/adult, resp.) against L. serricorne. The results indicate that the essential oil of C. camphora and its active compounds had the potential to be developed as natural fumigants and insecticides for control of L. serricorne.http://dx.doi.org/10.1155/2014/963729
spellingShingle Hai Ping Chen
Kai Yang
Chun Xue You
Ning Lei
Rui Qi Sun
Zhu Feng Geng
Ping Ma
Qian Cai
Shu Shan Du
Zhi Wei Deng
Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamomum camphora Leaves against Lasioderma serricorne
Journal of Chemistry
title Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamomum camphora Leaves against Lasioderma serricorne
title_full Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamomum camphora Leaves against Lasioderma serricorne
title_fullStr Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamomum camphora Leaves against Lasioderma serricorne
title_full_unstemmed Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamomum camphora Leaves against Lasioderma serricorne
title_short Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamomum camphora Leaves against Lasioderma serricorne
title_sort chemical constituents and insecticidal activities of the essential oil of cinnamomum camphora leaves against lasioderma serricorne
url http://dx.doi.org/10.1155/2014/963729
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