Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum: A Literature Review
Abstract. The recent increase in placenta accreta spectrum has been correlated with a rise in the rate of cesarean sections. A recent study provides evidence that hampered wound healing results in cesarean scar defects that lead to a failure in the normal process of decidualization and deeper adhere...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Health
2024-04-01
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| Series: | Maternal-Fetal Medicine |
| Online Access: | http://journals.lww.com/10.1097/FM9.0000000000000221 |
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| author | Putri Mirani Peby Maulina Lestari Krisna Murti Iche Andriyani Liberty Hana Andrina Cindy Kesty Bella Stevanny Yang Pan Jue Li |
| author_facet | Putri Mirani Peby Maulina Lestari Krisna Murti Iche Andriyani Liberty Hana Andrina Cindy Kesty Bella Stevanny Yang Pan Jue Li |
| author_sort | Putri Mirani |
| collection | DOAJ |
| description | Abstract. The recent increase in placenta accreta spectrum has been correlated with a rise in the rate of cesarean sections. A recent study provides evidence that hampered wound healing results in cesarean scar defects that lead to a failure in the normal process of decidualization and deeper adherence of trophoblasts. Matrix metalloproteinase (MMP) is crucial in every step of wound healing as it alters the wound matrix, facilitating cell migration, as well as tissue remodeling. MMP-9 expression is higher in placental and decidual tissue in cases of placenta accreta. Based on these findings, assessment of MMP-9 expression can shed new light on the etiopathology of placenta accreta spectrum disorder and can be a potential diagnostic marker. |
| format | Article |
| id | doaj-art-dc62f6959e0943db9b696939b9ed9bd4 |
| institution | DOAJ |
| issn | 2096-6954 2641-5895 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wolters Kluwer Health |
| record_format | Article |
| series | Maternal-Fetal Medicine |
| spelling | doaj-art-dc62f6959e0943db9b696939b9ed9bd42025-08-20T03:12:22ZengWolters Kluwer HealthMaternal-Fetal Medicine2096-69542641-58952024-04-01629710110.1097/FM9.0000000000000221202404000-00006Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum: A Literature ReviewPutri Mirani0Peby Maulina Lestari1Krisna Murti2Iche Andriyani Liberty3Hana Andrina4Cindy Kesty5Bella Stevanny6Yang PanJue Li1 Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya University, Palembang, South Sumatera, Indonesia1 Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya University, Palembang, South Sumatera, Indonesia2 Division of Hematolymphoid and Endocrinology, Department of Pathological Anatomy, Dr. Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya University, Palembang, Indonesia3 Department of Public Health and Community Medicine, Faculty of Medicine, Sriwijaya University, Palembang, Indonesia4 Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya University, Palembang, South Sumatera, Indonesia.4 Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya University, Palembang, South Sumatera, Indonesia.4 Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya University, Palembang, South Sumatera, Indonesia.Abstract. The recent increase in placenta accreta spectrum has been correlated with a rise in the rate of cesarean sections. A recent study provides evidence that hampered wound healing results in cesarean scar defects that lead to a failure in the normal process of decidualization and deeper adherence of trophoblasts. Matrix metalloproteinase (MMP) is crucial in every step of wound healing as it alters the wound matrix, facilitating cell migration, as well as tissue remodeling. MMP-9 expression is higher in placental and decidual tissue in cases of placenta accreta. Based on these findings, assessment of MMP-9 expression can shed new light on the etiopathology of placenta accreta spectrum disorder and can be a potential diagnostic marker.http://journals.lww.com/10.1097/FM9.0000000000000221 |
| spellingShingle | Putri Mirani Peby Maulina Lestari Krisna Murti Iche Andriyani Liberty Hana Andrina Cindy Kesty Bella Stevanny Yang Pan Jue Li Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum: A Literature Review Maternal-Fetal Medicine |
| title | Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum: A Literature Review |
| title_full | Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum: A Literature Review |
| title_fullStr | Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum: A Literature Review |
| title_full_unstemmed | Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum: A Literature Review |
| title_short | Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum: A Literature Review |
| title_sort | matrix metalloproteinase 9 in the etiopathogenesis of placenta accreta spectrum a literature review |
| url | http://journals.lww.com/10.1097/FM9.0000000000000221 |
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