TET2 orchestrates YAP signaling to potentiate targetable vulnerability in hepatocellular carcinoma

TET2 orchestrates YAP signaling to potentiate targetable vulnerability in hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) is a leading cause of global cancer-associated mortality. Although various therapies have substantially ameliorated clinical outcome, patients invariably suffer from cancer relapse, highlighting the need for more optimized therapeutic strategies. Here, we repo...

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Main Authors: Jing He, Mingen Lin, Fei Teng, Xue Sun, Ziyin Tian, Jiaxi Li, Yan Ma, Yue Dai, Yi Gao, Hongchen Li, Tongguan Tian, Kai Xu, Xinxing Li, Lei Lv, Yanping Xu
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07745-3
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