Evaluation of Methods Employed in Establishing Preclinical Similarity of Adalimumab Biosimilars

Adalimumab, marketed as Humira, is a fully humanized monoclonal antibody that blocks the activity of tumor necrosis factor-alpha and is used in treating several autoimmune disorders. As one of the top-grossing pharmaceuticals, its global sales surpassed $20 billion in 2023, leading to significant bi...

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Bibliographic Details
Main Authors: Ramya Nair, Naveen Krishnan, Vasudev Shenoy, Raviraja N. Seetharam
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advances in Pharmacological and Pharmaceutical Sciences
Online Access:http://dx.doi.org/10.1155/adpp/8816591
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