SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation.

SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation.

All lineages of SARS-CoV-2, the coronavirus responsible for the COVID-19 pandemic, contain mutations between amino acids 199 and 205 in the nucleocapsid (N) protein that are associated with increased infectivity. The effects of these mutations have been difficult to determine because N protein contr...

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Main Authors: Abdullah M Syed, Alison Ciling, Irene P Chen, Christopher R Carlson, Armin N Adly, Hannah S Martin, Taha Y Taha, Mir M Khalid, Nathan Price, Mehdi Bouhaddou, Manisha R Ummadi, Jack M Moen, Nevan J Krogan, David O Morgan, Melanie Ott, Jennifer A Doudna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-11-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012741&type=printable
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