Effects of macitentan and selexipag across prognostic age groups in patients with pulmonary arterial hypertension
BACKGROUND: Age affects disease severity and patient outcomes in pulmonary arterial hypertension. This post-hoc analysis identified prognostic age groups and associated macitentan/selexipag treatment effects. METHODS: Randomized trials evaluated macitentan (SERAPHIN; NCT00660179) and selexipag (GRIP...
Saved in:
Main Authors: | Richard Channick, MD, Sarah Medrek, MD, Marion Delcroix, MD, Sean Gaine, MD, Pavel Jansa, MD, PhD, Irene Lang, MD, Vallerie McLaughlin, MD, Sanjay Mehta, MD, Tomas Pulido, MD, Bhagavatula Sastry, MD, Rogerio Souza, MD, PhD, Adam Torbicki, MD, Carol Zhao, MS, Paul Strachan, MD, Peter Agron, PhD, Joseph Yen, PhD, Olivier Sitbon, MD, PhD |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
|
Series: | JHLT Open |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2950133424001472 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Solid Predominant Histology and High Podoplanin Expression in Cancer-Associated Fibroblast Predict Primary Resistance to Osimertinib in EGFR-Mutated Lung Adenocarcinoma
by: Yuji Uehara, MD, et al.
Published: (2025-03-01) -
A Phase I/II Study of Ultra-Hypofractionated Carbon-ion Radiation therapy for Low- and Intermediate-Risk Localized Prostate Cancer
by: Noriyuki Okonogi, MD, PhD, et al.
Published: (2025-03-01) -
Placental Vascular Malperfusion in Pregnancies With Congenital Heart Disease
by: Nour Rahnama, MD, et al.
Published: (2025-03-01) -
EGFR-Mutated Lung Adenocarcinoma With Li–Fraumeni Syndrome: The Imperative for Germline Testing in Patients With a Family History, a Case Report
by: Hiroyuki Fujii, MD, et al.
Published: (2025-02-01) -
Graft-Versus-Host Disease Sustains Coagulation Activity for two Years After Pediatric Allogeneic Hematopoietic Stem
Cell Transplantation
by: Satu Långström MD, PhD, et al.
Published: (2025-02-01)