Bisecting GlcNAc expression by bone marrow stromal cells modulates TGF-β1-driven macrophage polarization in myeloid leukemias

Bisecting GlcNAc expression by bone marrow stromal cells modulates TGF-β1-driven macrophage polarization in myeloid leukemias

Accumulating evidence have highlighted the critical role of tumor-associated macrophages (TAMs) in promoting immune evasion and disease progression in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Combined single-cell RNA sequencing, flow cytometry, and immunohistochemistry stud...

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Bibliographic Details
Main Authors: Jingjing Feng, Junjie Gou, Yi Wang, Wei Wei, Yihan Ma, Xueting Ren, Chongfu Zhao, Xiaoliang Cheng, Lei Lei, Zengqi Tan, Feng Guan, Xiang Li
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-05-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12071
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