Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview

Background: The treatment of chronic spontaneous urticaria (CSU) remains a challenge despite novel therapies such as omalizumab. With growing international interest in research on CSU, a comprehensive review of the global productivity, collaborations, and trending topics in CSU research may help inf...

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Main Authors: Hugo W.F. Mak, MBBS, MRes(Med), Freya K.L. Chung, MBBS, Philip H. Li, MD, Marcus Maurer, MD
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Allergy and Clinical Immunology: Global
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772829325000566
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author Hugo W.F. Mak, MBBS, MRes(Med)
Freya K.L. Chung, MBBS
Philip H. Li, MD
Marcus Maurer, MD
author_facet Hugo W.F. Mak, MBBS, MRes(Med)
Freya K.L. Chung, MBBS
Philip H. Li, MD
Marcus Maurer, MD
author_sort Hugo W.F. Mak, MBBS, MRes(Med)
collection DOAJ
description Background: The treatment of chronic spontaneous urticaria (CSU) remains a challenge despite novel therapies such as omalizumab. With growing international interest in research on CSU, a comprehensive review of the global productivity, collaborations, and trending topics in CSU research may help inform future directions in patient management. Objectives: This study aims to outline the trends in CSU research by using bibliometric analysis, focusing specifically on global productivity, collaborative efforts, and emerging research topics spanning from 1977 to 2023. Methods: Publications related to CSU, including original articles, reviews, and letters, were sourced from the Web of Science Core Collection, and statistical analyses were performed using the Bibliometrix package in R and IBM SPSS Statistics. Results: A total of 2940 publications from 77 countries were analyzed. CSU research activity has increased exponentially since 2010, with more than half of the publications (50.2% [1477 of 2940]) published since 2016. These publications appeared in allergy, immunology, and dermatology journals led predominantly by European, Asian, and American researchers. International collaborations rose from 11.3% to 22.2%. Shifts in research focus, such as a shift in treatments from antihistamines to omalizumab, and growing emphasis on quality of life were noted. Conclusion: This study revealed a dynamic and increasingly collaborative CSU research landscape, emphasizing the need for continuous global partnerships to enhance treatment outcomes and improve patients’ quality of life. Challenges regarding access to advanced therapies persist, highlighting the importance of expanding international collaborations and inclusive research practices.
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spelling doaj-art-dc384ccce6aa4f4ba7ddd2abc50d67822025-08-20T01:51:13ZengElsevierJournal of Allergy and Clinical Immunology: Global2772-82932025-05-014210045510.1016/j.jacig.2025.100455Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overviewHugo W.F. Mak, MBBS, MRes(Med)0Freya K.L. Chung, MBBS1Philip H. Li, MD2Marcus Maurer, MD3Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, ChinaDivision of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, ChinaDivision of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China; Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Hong Kong-Shenzhen Hospital, Guangdong, China; Corresponding author: Philip H. Li, MD, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Rd, Hong Kong.Fraunhofer Institute for Translational Medicine and Pharmacology, Immunology and Allergology, Berlin, GermanyBackground: The treatment of chronic spontaneous urticaria (CSU) remains a challenge despite novel therapies such as omalizumab. With growing international interest in research on CSU, a comprehensive review of the global productivity, collaborations, and trending topics in CSU research may help inform future directions in patient management. Objectives: This study aims to outline the trends in CSU research by using bibliometric analysis, focusing specifically on global productivity, collaborative efforts, and emerging research topics spanning from 1977 to 2023. Methods: Publications related to CSU, including original articles, reviews, and letters, were sourced from the Web of Science Core Collection, and statistical analyses were performed using the Bibliometrix package in R and IBM SPSS Statistics. Results: A total of 2940 publications from 77 countries were analyzed. CSU research activity has increased exponentially since 2010, with more than half of the publications (50.2% [1477 of 2940]) published since 2016. These publications appeared in allergy, immunology, and dermatology journals led predominantly by European, Asian, and American researchers. International collaborations rose from 11.3% to 22.2%. Shifts in research focus, such as a shift in treatments from antihistamines to omalizumab, and growing emphasis on quality of life were noted. Conclusion: This study revealed a dynamic and increasingly collaborative CSU research landscape, emphasizing the need for continuous global partnerships to enhance treatment outcomes and improve patients’ quality of life. Challenges regarding access to advanced therapies persist, highlighting the importance of expanding international collaborations and inclusive research practices.http://www.sciencedirect.com/science/article/pii/S2772829325000566Bibliometricchronicresearchspontaneoustrendsurticaria
spellingShingle Hugo W.F. Mak, MBBS, MRes(Med)
Freya K.L. Chung, MBBS
Philip H. Li, MD
Marcus Maurer, MD
Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview
Journal of Allergy and Clinical Immunology: Global
Bibliometric
chronic
research
spontaneous
trends
urticaria
title Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview
title_full Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview
title_fullStr Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview
title_full_unstemmed Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview
title_short Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview
title_sort global productivity international collaborations and research trends in chronic spontaneous urticaria a bibliometric overview
topic Bibliometric
chronic
research
spontaneous
trends
urticaria
url http://www.sciencedirect.com/science/article/pii/S2772829325000566
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