Successful Live Related Renal Transplantation in a 13 year old girl complicated with limited vascular access and fungal infections: A Case Report.

This case report illustrates a 13-year-old girl, a known case of hypertension (HTN) and End Stage Renal Disease (ESRD) secondary to Lupus nephritis (biopsy proven), who was commenced on maintenance hemodialysis twice weekly since two months. No permanent access was formed in the meantime as she had...

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Main Authors: Muhammad Tassaduq Khan, Sidra Rashid, Rashid bin Hamid
Format: Article
Language:English
Published: Liaquat University of Medical and Health Sciences 2024-12-01
Series:Liaquat Medical Research Journal
Subjects:
Online Access:http://121.52.154.206:80/index.php/LMRJ/article/view/1241
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author Muhammad Tassaduq Khan
Sidra Rashid
Rashid bin Hamid
author_facet Muhammad Tassaduq Khan
Sidra Rashid
Rashid bin Hamid
author_sort Muhammad Tassaduq Khan
collection DOAJ
description This case report illustrates a 13-year-old girl, a known case of hypertension (HTN) and End Stage Renal Disease (ESRD) secondary to Lupus nephritis (biopsy proven), who was commenced on maintenance hemodialysis twice weekly since two months. No permanent access was formed in the meantime as she had complicated vascular anatomy and multiple attempts leading to thrombosis. Arteriovenous Fistula (AVF) formation carried high risk of thrombosis, as well as the central access for hemodialysis was unattainable for long term use. She was admitted with central line bloodstream infection (CLABSI) and pneumonia which was non-responsive to IV antibiotics, her fungal markers showed elevated Galactomannan and beta D Glucan levels. These high levels necessitated the initiation of anti-fungal therapy and Voriconazole was started, which was later switched to Amphotericin B and Isavuconazole as no response was observed in earlier treatment. She underwent successful renal transplantation while her antifungal treatment was underway. This case reports a lifesaving transplant in a septic patient with limited central access for hemodialysis.
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spelling doaj-art-dc2fd3be43ad4633b25f18d98b71b9d32025-08-20T03:03:28ZengLiaquat University of Medical and Health SciencesLiaquat Medical Research Journal2664-57342709-58782024-12-016410.38106/LMRJ.2024.6.4-12Successful Live Related Renal Transplantation in a 13 year old girl complicated with limited vascular access and fungal infections: A Case Report.Muhammad Tassaduq Khan0Sidra Rashid1Rashid bin HamidDOW UNIVERSITY OF HEALTH SCIENCESDow university Hospital This case report illustrates a 13-year-old girl, a known case of hypertension (HTN) and End Stage Renal Disease (ESRD) secondary to Lupus nephritis (biopsy proven), who was commenced on maintenance hemodialysis twice weekly since two months. No permanent access was formed in the meantime as she had complicated vascular anatomy and multiple attempts leading to thrombosis. Arteriovenous Fistula (AVF) formation carried high risk of thrombosis, as well as the central access for hemodialysis was unattainable for long term use. She was admitted with central line bloodstream infection (CLABSI) and pneumonia which was non-responsive to IV antibiotics, her fungal markers showed elevated Galactomannan and beta D Glucan levels. These high levels necessitated the initiation of anti-fungal therapy and Voriconazole was started, which was later switched to Amphotericin B and Isavuconazole as no response was observed in earlier treatment. She underwent successful renal transplantation while her antifungal treatment was underway. This case reports a lifesaving transplant in a septic patient with limited central access for hemodialysis. http://121.52.154.206:80/index.php/LMRJ/article/view/1241transplant
spellingShingle Muhammad Tassaduq Khan
Sidra Rashid
Rashid bin Hamid
Successful Live Related Renal Transplantation in a 13 year old girl complicated with limited vascular access and fungal infections: A Case Report.
Liaquat Medical Research Journal
transplant
title Successful Live Related Renal Transplantation in a 13 year old girl complicated with limited vascular access and fungal infections: A Case Report.
title_full Successful Live Related Renal Transplantation in a 13 year old girl complicated with limited vascular access and fungal infections: A Case Report.
title_fullStr Successful Live Related Renal Transplantation in a 13 year old girl complicated with limited vascular access and fungal infections: A Case Report.
title_full_unstemmed Successful Live Related Renal Transplantation in a 13 year old girl complicated with limited vascular access and fungal infections: A Case Report.
title_short Successful Live Related Renal Transplantation in a 13 year old girl complicated with limited vascular access and fungal infections: A Case Report.
title_sort successful live related renal transplantation in a 13 year old girl complicated with limited vascular access and fungal infections a case report
topic transplant
url http://121.52.154.206:80/index.php/LMRJ/article/view/1241
work_keys_str_mv AT muhammadtassaduqkhan successfulliverelatedrenaltransplantationina13yearoldgirlcomplicatedwithlimitedvascularaccessandfungalinfectionsacasereport
AT sidrarashid successfulliverelatedrenaltransplantationina13yearoldgirlcomplicatedwithlimitedvascularaccessandfungalinfectionsacasereport
AT rashidbinhamid successfulliverelatedrenaltransplantationina13yearoldgirlcomplicatedwithlimitedvascularaccessandfungalinfectionsacasereport