Unlocking the power of swine gut bacteria: newly isolated Blautia strain and its metabolites inhibit the replication of Salmonella Typhimurium in macrophages and alleviate DSS-induced colitis in mice

Unlocking the power of swine gut bacteria: newly isolated Blautia strain and its metabolites inhibit the replication of Salmonella Typhimurium in macrophages and alleviate DSS-induced colitis in mice

Abstract Background Inflammatory bowel disease is a significant health concern for both humans and large-scale farm animals. In the quest for effective alternatives to antibiotics, next-generation probiotics (NGPs) have emerged as a promising option. The genus Blautia presents a rich source of poten...

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Bibliographic Details
Main Authors: Jiatong Wei, Yang Liu, Hua Li, Ze Lu, Yanjiao Liu, Yifan Zhang, Cong Lan, Aimin Wu, Jun He, Jingyi Cai, Gang Tian, Daiwen Chen, Bing Yu, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Hui Yan, Jiayong Tang, Huifen Wang, Quyuan Wang, Yuheng Luo
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Blautia hominis
Colitis
Inflammation
Macrophage
Online Access:https://doi.org/10.1186/s40104-025-01208-7
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