Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factors
Background: Knowledge of the incidence of ventilator-associated pneumonia (VAP) and its associated risk factors is imperative for the development and use of more effective preventive measures. Methodology: We performed a prospective study over a period of 15 months to determine the incidence and...
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The Journal of Infection in Developing Countries
2009-11-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/396 |
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| author | Noyal Mariya Joseph Sujatha Sistla Tarun Kumar Dutta Ashok Shankar Badhe Subhash Chandra Parija |
| author_facet | Noyal Mariya Joseph Sujatha Sistla Tarun Kumar Dutta Ashok Shankar Badhe Subhash Chandra Parija |
| author_sort | Noyal Mariya Joseph |
| collection | DOAJ |
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Background: Knowledge of the incidence of ventilator-associated pneumonia (VAP) and its associated risk factors is imperative for the development and use of more effective preventive measures.
Methodology: We performed a prospective study over a period of 15 months to determine the incidence and the risk factors for development of VAP in critically ill adult patients admitted in different intensive care units (ICUs) of Jawaharlal Institute of Post-graduate Medical Education and Research (JIPMER), a tertiary care hospital in Pondicherry, India.
Results: The incidence of VAP was 30.67 and 15.87 per 1,000 ventilator days in the two different ICUs. In our study 58.3% of the cases were late-onset VAP, while 41.7% were early-onset VAP. Univariate analysis indicated that the following were significantly associated with VAP: impaired consciousness, tracheostomy, re-intubation, emergency intubation, and nasogastric tube. Emergency intubation and intravenous sedatives were found to be the specific risk factors for early onset VAP, while tracheostomy and re-intubation were the independent predictors of late-onset VAP by multivariate logistic regression analysis.
Conclusions: Knowledge of these risk factors may be useful in implementing simple and effective preventive measures including non-invasive ventilation, precaution during emergency intubation, minimizing the occurrence of reintubation, avoidance of tracheostomy as far as possible, and minimization of sedation.
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| format | Article |
| id | doaj-art-dc28cb63b67640aeb182b6a563dbefcb |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2009-11-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-dc28cb63b67640aeb182b6a563dbefcb2025-08-20T02:57:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802009-11-0131010.3855/jidc.396Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factorsNoyal Mariya Joseph0Sujatha Sistla1Tarun Kumar Dutta2Ashok Shankar Badhe3Subhash Chandra Parija4Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), PondicherryDepartment of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), PondicherryDepartment of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), PondicherryDepartment of Anaesthesiology and Critical care, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), PondicherryDepartment of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry Background: Knowledge of the incidence of ventilator-associated pneumonia (VAP) and its associated risk factors is imperative for the development and use of more effective preventive measures. Methodology: We performed a prospective study over a period of 15 months to determine the incidence and the risk factors for development of VAP in critically ill adult patients admitted in different intensive care units (ICUs) of Jawaharlal Institute of Post-graduate Medical Education and Research (JIPMER), a tertiary care hospital in Pondicherry, India. Results: The incidence of VAP was 30.67 and 15.87 per 1,000 ventilator days in the two different ICUs. In our study 58.3% of the cases were late-onset VAP, while 41.7% were early-onset VAP. Univariate analysis indicated that the following were significantly associated with VAP: impaired consciousness, tracheostomy, re-intubation, emergency intubation, and nasogastric tube. Emergency intubation and intravenous sedatives were found to be the specific risk factors for early onset VAP, while tracheostomy and re-intubation were the independent predictors of late-onset VAP by multivariate logistic regression analysis. Conclusions: Knowledge of these risk factors may be useful in implementing simple and effective preventive measures including non-invasive ventilation, precaution during emergency intubation, minimizing the occurrence of reintubation, avoidance of tracheostomy as far as possible, and minimization of sedation. https://jidc.org/index.php/journal/article/view/396Ventilator-Associated Pneumoniarisk factorsEmergency intubationtracheostomy |
| spellingShingle | Noyal Mariya Joseph Sujatha Sistla Tarun Kumar Dutta Ashok Shankar Badhe Subhash Chandra Parija Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factors Journal of Infection in Developing Countries Ventilator-Associated Pneumonia risk factors Emergency intubation tracheostomy |
| title | Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factors |
| title_full | Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factors |
| title_fullStr | Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factors |
| title_full_unstemmed | Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factors |
| title_short | Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factors |
| title_sort | ventilator associated pneumonia in a tertiary care hospital in india incidence and risk factors |
| topic | Ventilator-Associated Pneumonia risk factors Emergency intubation tracheostomy |
| url | https://jidc.org/index.php/journal/article/view/396 |
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