In silico and in vitro evaluation of potential agonistic and antagonistic estrogenic and androgenic activities of pure cyanotoxins, microcystin-LR and cylindrospermopsin

In silico and in vitro evaluation of potential agonistic and antagonistic estrogenic and androgenic activities of pure cyanotoxins, microcystin-LR and cylindrospermopsin

The potential endocrine disruption activity of cyanotoxins, particularly their effects on estrogen and androgen receptors (ER, AR), remains poorly understood. In the present study, the potential agonistic/antagonistic estrogenic and androgenic activities of MC-LR and CYN have been determined for the...

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Bibliographic Details
Main Authors: Antonio Casas-Rodríguez, Antonio Cascajosa-Lira, María Puerto, Ana María Cameán, Angeles Jos
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
MC-LR
CYN
Estrogens
Androgens
Docking
Online Access:http://www.sciencedirect.com/science/article/pii/S014765132401532X
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