Genetic diversity of the immunoglobulin heavy chain locus in cohorts of patients affected with SARS-CoV-2

Genetic diversity of the immunoglobulin heavy chain locus in cohorts of patients affected with SARS-CoV-2

Abstract Background The Immunoglobulin Heavy Chain (IGH) genomic region is responsible for the production of circulating antibodies and warrants careful investigation for its association with COVID-19 characteristics. Multiple allelic variants within and across different IGH gene segments form a lim...

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Main Authors: Patrizia Malaspina, Carla Jodice, Bianca Maria Ciminelli, Michela Biancolella, Vito Luigi Colona, Andrea Latini, Francesca Leonardis, Paola Rogliani, Antonio Novelli, Giuseppe Novelli, Andrea Novelletto
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Human Genomics
Subjects:
Immunoglobulin heavy chain gene segments
SNP
Haplotypes
SARS-CoV-2
COVID-19
Online Access:https://doi.org/10.1186/s40246-025-00719-8
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