Role of BioCard Mycoplasma Immunoglobulin M Rapid Test in the Diagnosis of Mycoplasma pneumoniae Infection

Background: Mycoplasma pneumoniae is an important pathogenic bacterium that causes community-acquired pneumonia in children. Rapid and dependable laboratory diagnosis of M. pneumoniae infection is important for starting an appropriate antibiotic treatment. Currently, the serological testing for dete...

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Main Authors: Ta-Yu Liu, Hong-Ren Yu, Wei-Ju Lee, Chih-Min Tsai, Kuang-Che Kuo, Chih-Hao Chang, Yu-Tsun Su, Sui-Ching Wang, Chen-Kuang Niu, Kai-Sheng Hsieh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Pediatric Respirology and Critical Care Medicine
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Online Access:https://journals.lww.com/10.4103/prcm.prcm_30_17
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Summary:Background: Mycoplasma pneumoniae is an important pathogenic bacterium that causes community-acquired pneumonia in children. Rapid and dependable laboratory diagnosis of M. pneumoniae infection is important for starting an appropriate antibiotic treatment. Currently, the serological testing for detection of M. pneumoniae immunoglobulin M (IgM) has been used to determine the presence of an acute infection, the results of which, depending on the laboratory facility, are not available immediately. Therefore, an optimal and instant detection method is needed to facilitate a more accurate diagnosis, which leads to the appropriate treatment of patients with M. pneumoniae-related pneumonia and reduces rates of resistance to antibiotics because of their misuse. Aims: Here, we investigated the clinical diagnostic value of a rapid detection kit for M. pneumoniae-specific IgM antibody, the BioCard Mycoplasma IgM rapid test, in the detection of a Mycoplasma infection in children. Material and Method: 44 pediatric patients with clinically suspected Mycoplasma infection were enrolled for study. Result: Among 82 Mycoplasma IgM-positive samples, 51 samples were detected to be positive using the BioCard rapid test. The sensitivity and specifi city of the kit were 62.20% (51/82) and 100% (16/16), respectively. The positive and negative predictive values were 100% (51/51) and 34.04% (16/47), respectively. Conslusion: In conclusion, the BioCard Mycoplasma IgM rapid test provides an accurate point-of-care diagnosis for M. pneumonia infection.
ISSN:2543-0343
2543-0351