Reconfigurable Ultra-Miniaturized MIMO Antenna for Tissue-Independent Communication in Injectable Medical Implants

This article introduces a compact, reconfigurable multiple-input-multiple-output (MIMO) antenna tailored for injectable in-body implants, designed to operate efficiently in the 2.45 GHz industrial, scientific, and medical (ISM) band, ensuring consistent performance regardless of the host tissue type...

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Main Authors: L. Harlan, M. Susila, Sachin Kumar, Hyun Chul Choi, Kang Wook Kim
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
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Online Access:https://ieeexplore.ieee.org/document/10855997/
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author L. Harlan
M. Susila
Sachin Kumar
Hyun Chul Choi
Kang Wook Kim
author_facet L. Harlan
M. Susila
Sachin Kumar
Hyun Chul Choi
Kang Wook Kim
author_sort L. Harlan
collection DOAJ
description This article introduces a compact, reconfigurable multiple-input-multiple-output (MIMO) antenna tailored for injectable in-body implants, designed to operate efficiently in the 2.45 GHz industrial, scientific, and medical (ISM) band, ensuring consistent performance regardless of the host tissue type, such as muscle or fat. The antenna design achieves miniaturization using meandered lines and shorting pins, while reconfigurability is obtained by adjusting the meandered length with an ON-OFF switch (diode). When the diode is ON, the antenna&#x2019;s meandered length is increased, thereby extending its effective length and enabling resonance in the 2.42&#x2013;2.48 GHz range for fat tissues. Conversely, when the diode is OFF, the effective length is reduced, allowing the same antenna to operate within the 2.38&#x2013;2.48 GHz range in muscle tissues. The proposed antenna, fabricated on a flexible polyimide substrate (<inline-formula> <tex-math notation="LaTeX">$\varepsilon _{r} =3.5$ </tex-math></inline-formula>), with overall dimensions of 5 mm <inline-formula> <tex-math notation="LaTeX">$\times 2$ </tex-math></inline-formula> mm <inline-formula> <tex-math notation="LaTeX">$\times 0.05$ </tex-math></inline-formula> mm, is enclosed within a biocompatible polyimide casing. The antenna&#x2019;s performance is evaluated through simulations in homogeneous single-layer (fat/muscle) and three-layer (skin, fat, and muscle) phantoms, along with a realistic heterogeneous hand model, and validated through an ex-vivo setup, which includes fabricating the antenna prototype and measuring its performance in pork meat and a phantom solution. This innovative, miniaturized, tissue-independent MIMO antenna achieves isolation greater than 15 dB via orthogonal arrangement and 1 mm element spacing, with impedance bandwidths of 60 MHz in fat and 100 MHz in muscle. Furthermore, MIMO characteristics are evaluated and antenna robustness and safety are verified through specific absorption rate measurements using voxel models, highlighting the antenna&#x2019;s suitability for injectable applications.
format Article
id doaj-art-dc0966dab8434319be318d37de1001f9
institution Kabale University
issn 2169-3536
language English
publishDate 2025-01-01
publisher IEEE
record_format Article
series IEEE Access
spelling doaj-art-dc0966dab8434319be318d37de1001f92025-02-07T00:01:13ZengIEEEIEEE Access2169-35362025-01-0113226632267710.1109/ACCESS.2025.353578010855997Reconfigurable Ultra-Miniaturized MIMO Antenna for Tissue-Independent Communication in Injectable Medical ImplantsL. Harlan0https://orcid.org/0009-0009-9560-8441M. Susila1https://orcid.org/0000-0003-2773-4939Sachin Kumar2https://orcid.org/0000-0002-6260-6353Hyun Chul Choi3https://orcid.org/0000-0003-3128-6737Kang Wook Kim4https://orcid.org/0000-0002-3959-9191Department of Electronics and Communication Engineering, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, IndiaDepartment of Electronics and Communication Engineering, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, IndiaDepartment of Electronics and Communication Engineering, Galgotias College of Engineering and Technology, Greater Noida, Uttar Pradesh, IndiaSchool of Electronic and Electrical Engineering, Kyungpook National University, Daegu, Republic of KoreaSchool of Electronic and Electrical Engineering, Kyungpook National University, Daegu, Republic of KoreaThis article introduces a compact, reconfigurable multiple-input-multiple-output (MIMO) antenna tailored for injectable in-body implants, designed to operate efficiently in the 2.45 GHz industrial, scientific, and medical (ISM) band, ensuring consistent performance regardless of the host tissue type, such as muscle or fat. The antenna design achieves miniaturization using meandered lines and shorting pins, while reconfigurability is obtained by adjusting the meandered length with an ON-OFF switch (diode). When the diode is ON, the antenna&#x2019;s meandered length is increased, thereby extending its effective length and enabling resonance in the 2.42&#x2013;2.48 GHz range for fat tissues. Conversely, when the diode is OFF, the effective length is reduced, allowing the same antenna to operate within the 2.38&#x2013;2.48 GHz range in muscle tissues. The proposed antenna, fabricated on a flexible polyimide substrate (<inline-formula> <tex-math notation="LaTeX">$\varepsilon _{r} =3.5$ </tex-math></inline-formula>), with overall dimensions of 5 mm <inline-formula> <tex-math notation="LaTeX">$\times 2$ </tex-math></inline-formula> mm <inline-formula> <tex-math notation="LaTeX">$\times 0.05$ </tex-math></inline-formula> mm, is enclosed within a biocompatible polyimide casing. The antenna&#x2019;s performance is evaluated through simulations in homogeneous single-layer (fat/muscle) and three-layer (skin, fat, and muscle) phantoms, along with a realistic heterogeneous hand model, and validated through an ex-vivo setup, which includes fabricating the antenna prototype and measuring its performance in pork meat and a phantom solution. This innovative, miniaturized, tissue-independent MIMO antenna achieves isolation greater than 15 dB via orthogonal arrangement and 1 mm element spacing, with impedance bandwidths of 60 MHz in fat and 100 MHz in muscle. Furthermore, MIMO characteristics are evaluated and antenna robustness and safety are verified through specific absorption rate measurements using voxel models, highlighting the antenna&#x2019;s suitability for injectable applications.https://ieeexplore.ieee.org/document/10855997/Biomedical deviceflexible antennainjectable antennaMIMOreconfigurable antenna
spellingShingle L. Harlan
M. Susila
Sachin Kumar
Hyun Chul Choi
Kang Wook Kim
Reconfigurable Ultra-Miniaturized MIMO Antenna for Tissue-Independent Communication in Injectable Medical Implants
IEEE Access
Biomedical device
flexible antenna
injectable antenna
MIMO
reconfigurable antenna
title Reconfigurable Ultra-Miniaturized MIMO Antenna for Tissue-Independent Communication in Injectable Medical Implants
title_full Reconfigurable Ultra-Miniaturized MIMO Antenna for Tissue-Independent Communication in Injectable Medical Implants
title_fullStr Reconfigurable Ultra-Miniaturized MIMO Antenna for Tissue-Independent Communication in Injectable Medical Implants
title_full_unstemmed Reconfigurable Ultra-Miniaturized MIMO Antenna for Tissue-Independent Communication in Injectable Medical Implants
title_short Reconfigurable Ultra-Miniaturized MIMO Antenna for Tissue-Independent Communication in Injectable Medical Implants
title_sort reconfigurable ultra miniaturized mimo antenna for tissue independent communication in injectable medical implants
topic Biomedical device
flexible antenna
injectable antenna
MIMO
reconfigurable antenna
url https://ieeexplore.ieee.org/document/10855997/
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AT msusila reconfigurableultraminiaturizedmimoantennafortissueindependentcommunicationininjectablemedicalimplants
AT sachinkumar reconfigurableultraminiaturizedmimoantennafortissueindependentcommunicationininjectablemedicalimplants
AT hyunchulchoi reconfigurableultraminiaturizedmimoantennafortissueindependentcommunicationininjectablemedicalimplants
AT kangwookkim reconfigurableultraminiaturizedmimoantennafortissueindependentcommunicationininjectablemedicalimplants