Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive Impairment

Background Cognitive decline in dementia often leads to impaired activities of daily living (ADL), which worsens as the condition progresses. Although a complex rehabilitation program that includes exercise, cognitive tasks, and family guidance improves physical ability in people with dementia and m...

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Main Authors: Aiko Osawa, Shinichiro Maeshima, Masaki Kamiya, Ikue Ueda, Naoki Itoh, Izumi Kondo, Hidenori Arai
Format: Article
Language:English
Published: Korea Geriatrics Society 2025-06-01
Series:Annals of Geriatric Medicine and Research
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Online Access:http://www.e-agmr.org/upload/pdf/agmr-24-0158.pdf
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author Aiko Osawa
Shinichiro Maeshima
Masaki Kamiya
Ikue Ueda
Naoki Itoh
Izumi Kondo
Hidenori Arai
author_facet Aiko Osawa
Shinichiro Maeshima
Masaki Kamiya
Ikue Ueda
Naoki Itoh
Izumi Kondo
Hidenori Arai
author_sort Aiko Osawa
collection DOAJ
description Background Cognitive decline in dementia often leads to impaired activities of daily living (ADL), which worsens as the condition progresses. Although a complex rehabilitation program that includes exercise, cognitive tasks, and family guidance improves physical ability in people with dementia and mild cognitive impairment (MCI), the effects on cognitive function and ADL remain unclear. We conducted this study to clarify this point. Methods This retrospective observational study was conducted at the outpatient rehabilitation department of the National Center for Geriatrics and Gerontology, Japan. It analyzed 50 MCI and Alzheimer disease (AD) patients who participated in a holistic physico-cognitive rehabilitation (HPCR) program. The control group consisted of 50 patients matched by age, gender, disease, and Barthel Index (BI) from 963 MCI and AD patients who did not undergo HPCR. Cognitive function was assessed using the Mini-Mental State Examination, and ADL was evaluated with the BI. Results Both groups showed a significant decline in MMSE scores after 1 year. However, the intervention group maintained its ADL function, while the control group experienced a significant reduction in BI scores. Conclusion HPCR, combining exercise therapy and cognitive training, may help maintain ADL in patients with MCI and AD despite cognitive decline. This study suggests that rehabilitation plays a crucial role in sustaining daily functioning in dementia care.
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spelling doaj-art-dc056d477ae6407baf9516b802cc3e172025-08-20T02:37:24ZengKorea Geriatrics SocietyAnnals of Geriatric Medicine and Research2508-47982508-49092025-06-0129220721210.4235/agmr.24.01581189Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive ImpairmentAiko Osawa0Shinichiro Maeshima1Masaki Kamiya2Ikue Ueda3Naoki Itoh4Izumi Kondo5Hidenori Arai6 Department of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan Education and Innovation Center, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan Department of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan Department of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan Department of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan Department of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan National Center for Geriatrics and Gerontology, Obu, Aichi, JapanBackground Cognitive decline in dementia often leads to impaired activities of daily living (ADL), which worsens as the condition progresses. Although a complex rehabilitation program that includes exercise, cognitive tasks, and family guidance improves physical ability in people with dementia and mild cognitive impairment (MCI), the effects on cognitive function and ADL remain unclear. We conducted this study to clarify this point. Methods This retrospective observational study was conducted at the outpatient rehabilitation department of the National Center for Geriatrics and Gerontology, Japan. It analyzed 50 MCI and Alzheimer disease (AD) patients who participated in a holistic physico-cognitive rehabilitation (HPCR) program. The control group consisted of 50 patients matched by age, gender, disease, and Barthel Index (BI) from 963 MCI and AD patients who did not undergo HPCR. Cognitive function was assessed using the Mini-Mental State Examination, and ADL was evaluated with the BI. Results Both groups showed a significant decline in MMSE scores after 1 year. However, the intervention group maintained its ADL function, while the control group experienced a significant reduction in BI scores. Conclusion HPCR, combining exercise therapy and cognitive training, may help maintain ADL in patients with MCI and AD despite cognitive decline. This study suggests that rehabilitation plays a crucial role in sustaining daily functioning in dementia care.http://www.e-agmr.org/upload/pdf/agmr-24-0158.pdfalzheimer diseasemild cognitive impairmentactivities of daily livingrehabilitationaged
spellingShingle Aiko Osawa
Shinichiro Maeshima
Masaki Kamiya
Ikue Ueda
Naoki Itoh
Izumi Kondo
Hidenori Arai
Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive Impairment
Annals of Geriatric Medicine and Research
alzheimer disease
mild cognitive impairment
activities of daily living
rehabilitation
aged
title Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive Impairment
title_full Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive Impairment
title_fullStr Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive Impairment
title_full_unstemmed Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive Impairment
title_short Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive Impairment
title_sort intervention effects of the holistic physio cognitive rehabilitation for alzheimer disease and mild cognitive impairment
topic alzheimer disease
mild cognitive impairment
activities of daily living
rehabilitation
aged
url http://www.e-agmr.org/upload/pdf/agmr-24-0158.pdf
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