γ-Synuclein antibodies have neuroprotective potential on neuroretinal cells via proteins of the mitochondrial apoptosis pathway.
The family of synuclein proteins (α, β and γ) are related to neurodegenerative disease e.g. Parkinson disease and Morbus Alzheimer. Additionally, a connection between γ-synuclein and glaucoma, a neurodegenerative disease characterized by a progressive loss of retinal ganglion cells, which finally le...
Saved in:
| Main Authors: | Corina Wilding, Katharina Bell, Sabine Beck, Sebastian Funke, Norbert Pfeiffer, Franz H Grus |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090737&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A Review Article on Neuroretinitis
by: Franz Marie Cruz, MD, DPBO, et al.
Published: (2018-06-01) -
Targeting glial fibrillary acidic protein in glaucoma: a monoclonal antibody approach to modulate glial reactivity and neuroinflammation for neuroprotection
by: Chaoqiang Guan, et al.
Published: (2025-06-01) -
Bilateral Idiopathic Neuroretinitis
by: Cosmin Adrian Teodoru, et al.
Published: (2024-10-01) -
Anti-TNFα and Anti-IL-1β Monoclonal Antibodies Preserve BV-2 Microglial Homeostasis Under Hypoxia by Mitigating Inflammatory Reactivity and ATF4/MAPK-Mediated Apoptosis
by: Linglin Zhang, et al.
Published: (2025-03-01) -
Neuroretinitis and Covid19: An Astounding Correlation
by: Dhaivat Shah, et al.
Published: (2021-10-01)