A multi-center, cross-sectional study on the burden of infectious keratitis in China.
<h4>Objective</h4>To understand the prevalence and demographic characteristics of infectious keratitis and infectious corneal blindness.<h4>Methods</h4>A multi-center, population-based cross-sectional study was conducted from January 1 to August 31, 2010. A total of 191,242 i...
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Public Library of Science (PLoS)
2014-01-01
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| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113843&type=printable |
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| author | Xiusheng Song Lixin Xie Xiaodong Tan Zhichong Wang Yanning Yang Yuansheng Yuan Yingping Deng Shaoying Fu Jianjiang Xu Xuguang Sun Xunlun Sheng Qing Wang |
| author_facet | Xiusheng Song Lixin Xie Xiaodong Tan Zhichong Wang Yanning Yang Yuansheng Yuan Yingping Deng Shaoying Fu Jianjiang Xu Xuguang Sun Xunlun Sheng Qing Wang |
| author_sort | Xiusheng Song |
| collection | DOAJ |
| description | <h4>Objective</h4>To understand the prevalence and demographic characteristics of infectious keratitis and infectious corneal blindness.<h4>Methods</h4>A multi-center, population-based cross-sectional study was conducted from January 1 to August 31, 2010. A total of 191,242 individuals of all age groups from 10 geographically representative provinces were sampled using stratified, multi-stage, random and systematic sampling procedures. A majority, 168,673 (88.2%), of those sampled participated in the study. The examination protocol included a structured interview, visual acuity testing, an external eye examination, and an anterior segment examination using a slit lamp. The causes and sequelae of corneal disease were identified using uniform customized protocols. Blindness in one eye caused by infectious keratitis was defined as infectious corneal blindness.<h4>Results</h4>The prevalence of past and active infectious keratitis was 0.192% (95% confidence interval [CI], 0.171-0.213%), and the prevalence of viral, bacterial, and fungal keratitis was 0.11%, 0.075%, and 0.007%, respectively. There were 138 cases of infectious corneal blindness in at least one eye in the study population (prevalence of 0.082% [95%CI, 0.068%-0.095%]). Statistical analysis suggested that ocular trauma, alcoholic consumption, low socioeconomic levels, advanced age, and poor education were risk factors for infectious corneal blindness.<h4>Conclusions</h4>Infectious keratitis is the leading cause of corneal blindness in China. Eye care strategies should focus on the prevention and rehabilitation of infectious corneal blindness. |
| format | Article |
| id | doaj-art-dc020b76cbb64fd0b5f657fc515750a8 |
| institution | DOAJ |
| issn | 1932-6203 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-dc020b76cbb64fd0b5f657fc515750a82025-08-20T03:00:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-01912e11384310.1371/journal.pone.0113843A multi-center, cross-sectional study on the burden of infectious keratitis in China.Xiusheng SongLixin XieXiaodong TanZhichong WangYanning YangYuansheng YuanYingping DengShaoying FuJianjiang XuXuguang SunXunlun ShengQing Wang<h4>Objective</h4>To understand the prevalence and demographic characteristics of infectious keratitis and infectious corneal blindness.<h4>Methods</h4>A multi-center, population-based cross-sectional study was conducted from January 1 to August 31, 2010. A total of 191,242 individuals of all age groups from 10 geographically representative provinces were sampled using stratified, multi-stage, random and systematic sampling procedures. A majority, 168,673 (88.2%), of those sampled participated in the study. The examination protocol included a structured interview, visual acuity testing, an external eye examination, and an anterior segment examination using a slit lamp. The causes and sequelae of corneal disease were identified using uniform customized protocols. Blindness in one eye caused by infectious keratitis was defined as infectious corneal blindness.<h4>Results</h4>The prevalence of past and active infectious keratitis was 0.192% (95% confidence interval [CI], 0.171-0.213%), and the prevalence of viral, bacterial, and fungal keratitis was 0.11%, 0.075%, and 0.007%, respectively. There were 138 cases of infectious corneal blindness in at least one eye in the study population (prevalence of 0.082% [95%CI, 0.068%-0.095%]). Statistical analysis suggested that ocular trauma, alcoholic consumption, low socioeconomic levels, advanced age, and poor education were risk factors for infectious corneal blindness.<h4>Conclusions</h4>Infectious keratitis is the leading cause of corneal blindness in China. Eye care strategies should focus on the prevention and rehabilitation of infectious corneal blindness.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113843&type=printable |
| spellingShingle | Xiusheng Song Lixin Xie Xiaodong Tan Zhichong Wang Yanning Yang Yuansheng Yuan Yingping Deng Shaoying Fu Jianjiang Xu Xuguang Sun Xunlun Sheng Qing Wang A multi-center, cross-sectional study on the burden of infectious keratitis in China. PLoS ONE |
| title | A multi-center, cross-sectional study on the burden of infectious keratitis in China. |
| title_full | A multi-center, cross-sectional study on the burden of infectious keratitis in China. |
| title_fullStr | A multi-center, cross-sectional study on the burden of infectious keratitis in China. |
| title_full_unstemmed | A multi-center, cross-sectional study on the burden of infectious keratitis in China. |
| title_short | A multi-center, cross-sectional study on the burden of infectious keratitis in China. |
| title_sort | multi center cross sectional study on the burden of infectious keratitis in china |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113843&type=printable |
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