Interaction of a new antiviral and antitumor photosensitizer hypericin with human serum albumin: molecular modeling study

Molecular modeling has been employed to study the interaction of hypericin (Hyp) with human serum albumin (HSA). The structural model for Hyp/HSA complex is presented. Our results indicate that Hyp is bound in II A subdomain of HSA close to the tryptophan 214 (Trp214) (distance 5.12 Å between the ce...

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Bibliographic Details
Main Authors: Jozef Hritz, Jozef Ulicny, Pavol Miskovsky
Format: Article
Language:English
Published: Wiley 2002-01-01
Series:International Journal of Photoenergy
Online Access:http://dx.doi.org/10.1155/S1110662X02000089
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