A Differential Approach to Choosing Extracorporeal Detoxification Methods for Abdominal Sepsis
A differential approach to choosing the methods of extracorporeal detoxification in the complex treatment of abdominal sepsis in the context of endogenous intoxication in order to enhance the efficiency of medical measures was pathogeneti-cally substantiated. In 51 patients diagnosed as having abdom...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2005-08-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1246 |
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| author | L. Ye Shukevich Yu. A. Churlyaev Ye. V. Grigoryev D. L. Shukevich K. N. Kondyukov A. S. Razumov |
| author_facet | L. Ye Shukevich Yu. A. Churlyaev Ye. V. Grigoryev D. L. Shukevich K. N. Kondyukov A. S. Razumov |
| author_sort | L. Ye Shukevich |
| collection | DOAJ |
| description | A differential approach to choosing the methods of extracorporeal detoxification in the complex treatment of abdominal sepsis in the context of endogenous intoxication in order to enhance the efficiency of medical measures was pathogeneti-cally substantiated. In 51 patients diagnosed as having abdominal sepsis, the latter was characterized as the endogenous intoxication syndrome in relation to the accumulation of low and medium molecular-weight substances (plasma and red blood cells) in the body and their physiological elimination with urine. An original formula was used to calculate the integral marker – the endogenous intoxication index correlating with the routine severity rating scales APACHE II and SOFA and reflecting the severity of endotoxicosis. According to the values of the endogenous intoxication index and to the sum of scores by the APACHE II and SOFA scales, the patients were divided into 3 groups of the clinicopathogenetic types of endogenous intoxication. According to the type of endogenous intoxication, the authors proposed a differential approach to choosing the modes of efferent therapy for abdominal sepsis: high-volume plasmapheresis in the subcompensated type and prolonged venovenous hemofiltration, which improved the results of treatment and reduced mortality rates. |
| format | Article |
| id | doaj-art-dbf6b1cb68484b619c270ea46040a89e |
| institution | DOAJ |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2005-08-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-dbf6b1cb68484b619c270ea46040a89e2025-08-20T03:18:50ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102005-08-0114364010.15360/1813-9779-2005-4-36-401246A Differential Approach to Choosing Extracorporeal Detoxification Methods for Abdominal SepsisL. Ye Shukevich0Yu. A. Churlyaev1Ye. V. Grigoryev2D. L. Shukevich3K. N. Kondyukov4A. S. Razumov5Kemerovo Regional Clinical Hospital; Kemerovo State Medical Academy, Ministry of Health of the Russian Federation; Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo Regional Clinical Hospital; Kemerovo State Medical Academy, Ministry of Health of the Russian Federation; Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo Regional Clinical Hospital; Kemerovo State Medical Academy, Ministry of Health of the Russian Federation; Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo Regional Clinical Hospital; Kemerovo State Medical Academy, Ministry of Health of the Russian Federation; Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo Regional Clinical Hospital; Kemerovo State Medical Academy, Ministry of Health of the Russian Federation; Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo Regional Clinical Hospital; Kemerovo State Medical Academy, Ministry of Health of the Russian Federation; Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskA differential approach to choosing the methods of extracorporeal detoxification in the complex treatment of abdominal sepsis in the context of endogenous intoxication in order to enhance the efficiency of medical measures was pathogeneti-cally substantiated. In 51 patients diagnosed as having abdominal sepsis, the latter was characterized as the endogenous intoxication syndrome in relation to the accumulation of low and medium molecular-weight substances (plasma and red blood cells) in the body and their physiological elimination with urine. An original formula was used to calculate the integral marker – the endogenous intoxication index correlating with the routine severity rating scales APACHE II and SOFA and reflecting the severity of endotoxicosis. According to the values of the endogenous intoxication index and to the sum of scores by the APACHE II and SOFA scales, the patients were divided into 3 groups of the clinicopathogenetic types of endogenous intoxication. According to the type of endogenous intoxication, the authors proposed a differential approach to choosing the modes of efferent therapy for abdominal sepsis: high-volume plasmapheresis in the subcompensated type and prolonged venovenous hemofiltration, which improved the results of treatment and reduced mortality rates.https://www.reanimatology.com/rmt/article/view/1246 |
| spellingShingle | L. Ye Shukevich Yu. A. Churlyaev Ye. V. Grigoryev D. L. Shukevich K. N. Kondyukov A. S. Razumov A Differential Approach to Choosing Extracorporeal Detoxification Methods for Abdominal Sepsis Общая реаниматология |
| title | A Differential Approach to Choosing Extracorporeal Detoxification Methods for Abdominal Sepsis |
| title_full | A Differential Approach to Choosing Extracorporeal Detoxification Methods for Abdominal Sepsis |
| title_fullStr | A Differential Approach to Choosing Extracorporeal Detoxification Methods for Abdominal Sepsis |
| title_full_unstemmed | A Differential Approach to Choosing Extracorporeal Detoxification Methods for Abdominal Sepsis |
| title_short | A Differential Approach to Choosing Extracorporeal Detoxification Methods for Abdominal Sepsis |
| title_sort | differential approach to choosing extracorporeal detoxification methods for abdominal sepsis |
| url | https://www.reanimatology.com/rmt/article/view/1246 |
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