The role of lncRNA and miRNA in the pathogenesis of renal fibrosis
Renal fibrosis (RF) is a common pathological process leading to end-stage renal failure in chronic kidney disease, with a complex molecular mechanism. Long non-coding RNA (lncRNA) and mi-croRNA (miRNA) are the main non-coding RNAs, affecting disease processes, cellular homeostasis and development th...
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| Format: | Article |
| Language: | zho |
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Editorial Office of New Medicine
2023-04-01
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| Series: | Yixue xinzhi zazhi |
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| Online Access: | https://yxxz.whuznhmedj.com/futureApi/storage/attach/2304/qWBnKQmrMezqLTlxSyi0lWa2SZrskw6cXwsuMdum.pdf |
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| _version_ | 1846109531059257344 |
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| author | Liang CHANG Yu-Ming LI Jin-Peng HU |
| author_facet | Liang CHANG Yu-Ming LI Jin-Peng HU |
| author_sort | Liang CHANG |
| collection | DOAJ |
| description | Renal fibrosis (RF) is a common pathological process leading to end-stage renal failure in chronic kidney disease, with a complex molecular mechanism. Long non-coding RNA (lncRNA) and mi-croRNA (miRNA) are the main non-coding RNAs, affecting disease processes, cellular homeostasis and development through a variety of mechanisms. An increasing number of studies show that lncRNA and miRNA have high application value as biomarkers for RF, including the treatment of renal fibrosis disease based on these and the early detection of RF disease. Therefore, this paper reviews the research progress of lncRNA, miRNA and their interaction in RF. |
| format | Article |
| id | doaj-art-dbf39b05a9784d25b3ce5b2ddb4bb673 |
| institution | Kabale University |
| issn | 1004-5511 |
| language | zho |
| publishDate | 2023-04-01 |
| publisher | Editorial Office of New Medicine |
| record_format | Article |
| series | Yixue xinzhi zazhi |
| spelling | doaj-art-dbf39b05a9784d25b3ce5b2ddb4bb6732024-12-25T10:14:33ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112023-04-0133214915610.12173/j.issn.1004-5511.2022060106355The role of lncRNA and miRNA in the pathogenesis of renal fibrosisLiang CHANGYu-Ming LIJin-Peng HURenal fibrosis (RF) is a common pathological process leading to end-stage renal failure in chronic kidney disease, with a complex molecular mechanism. Long non-coding RNA (lncRNA) and mi-croRNA (miRNA) are the main non-coding RNAs, affecting disease processes, cellular homeostasis and development through a variety of mechanisms. An increasing number of studies show that lncRNA and miRNA have high application value as biomarkers for RF, including the treatment of renal fibrosis disease based on these and the early detection of RF disease. Therefore, this paper reviews the research progress of lncRNA, miRNA and their interaction in RF.https://yxxz.whuznhmedj.com/futureApi/storage/attach/2304/qWBnKQmrMezqLTlxSyi0lWa2SZrskw6cXwsuMdum.pdfrenal fibrosislncrnamirna |
| spellingShingle | Liang CHANG Yu-Ming LI Jin-Peng HU The role of lncRNA and miRNA in the pathogenesis of renal fibrosis Yixue xinzhi zazhi renal fibrosis lncrna mirna |
| title | The role of lncRNA and miRNA in the pathogenesis of renal fibrosis |
| title_full | The role of lncRNA and miRNA in the pathogenesis of renal fibrosis |
| title_fullStr | The role of lncRNA and miRNA in the pathogenesis of renal fibrosis |
| title_full_unstemmed | The role of lncRNA and miRNA in the pathogenesis of renal fibrosis |
| title_short | The role of lncRNA and miRNA in the pathogenesis of renal fibrosis |
| title_sort | role of lncrna and mirna in the pathogenesis of renal fibrosis |
| topic | renal fibrosis lncrna mirna |
| url | https://yxxz.whuznhmedj.com/futureApi/storage/attach/2304/qWBnKQmrMezqLTlxSyi0lWa2SZrskw6cXwsuMdum.pdf |
| work_keys_str_mv | AT liangchang theroleoflncrnaandmirnainthepathogenesisofrenalfibrosis AT yumingli theroleoflncrnaandmirnainthepathogenesisofrenalfibrosis AT jinpenghu theroleoflncrnaandmirnainthepathogenesisofrenalfibrosis AT liangchang roleoflncrnaandmirnainthepathogenesisofrenalfibrosis AT yumingli roleoflncrnaandmirnainthepathogenesisofrenalfibrosis AT jinpenghu roleoflncrnaandmirnainthepathogenesisofrenalfibrosis |