The role of lncRNA and miRNA in the pathogenesis of renal fibrosis
Renal fibrosis (RF) is a common pathological process leading to end-stage renal failure in chronic kidney disease, with a complex molecular mechanism. Long non-coding RNA (lncRNA) and mi-croRNA (miRNA) are the main non-coding RNAs, affecting disease processes, cellular homeostasis and development th...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of New Medicine
2023-04-01
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| Series: | Yixue xinzhi zazhi |
| Subjects: | |
| Online Access: | https://yxxz.whuznhmedj.com/futureApi/storage/attach/2304/qWBnKQmrMezqLTlxSyi0lWa2SZrskw6cXwsuMdum.pdf |
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| Summary: | Renal fibrosis (RF) is a common pathological process leading to end-stage renal failure in chronic kidney disease, with a complex molecular mechanism. Long non-coding RNA (lncRNA) and mi-croRNA (miRNA) are the main non-coding RNAs, affecting disease processes, cellular homeostasis and development through a variety of mechanisms. An increasing number of studies show that lncRNA and miRNA have high application value as biomarkers for RF, including the treatment of renal fibrosis disease based on these and the early detection of RF disease. Therefore, this paper reviews the research progress of lncRNA, miRNA and their interaction in RF. |
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| ISSN: | 1004-5511 |