Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré Syndrome

Background. Guillain-Barré syndrome (GBS) has many variants with distinct presentations. Ptosis as an initial presentation is rare. Case Report. We describe a young female with bilateral ptosis without ophthalmoplegia as the initial presentation of Guillain-Barré ptosis in an anti-GQ1b IgG antibody...

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Main Authors: Yahia Z. Imam, Dirk Deleu
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2013/178291
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author Yahia Z. Imam
Dirk Deleu
author_facet Yahia Z. Imam
Dirk Deleu
author_sort Yahia Z. Imam
collection DOAJ
description Background. Guillain-Barré syndrome (GBS) has many variants with distinct presentations. Ptosis as an initial presentation is rare. Case Report. We describe a young female with bilateral ptosis without ophthalmoplegia as the initial presentation of Guillain-Barré ptosis in an anti-GQ1b IgG antibody negative patient with a favorable outcome to intravenous immunoglobulins. Objectives. Our paper highlights the importance of recognizing GBS as a potential etiology in a patient presenting with isolated ptosis, particularly since the course of GBS can be more dramatic than in the anti-GBQ1b syndromes such as ophthalmoparesis without ataxia and Miller Fisher syndrome or ocular myasthenia. Conclusion. This is the first paper of anti-GBQ1b antibody negative GBS presenting with isolated ptosis without ophthalmoparesis. GBS should be included in the list of differential diagnosis of such presentations.
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spelling doaj-art-dbf17c264f424a5f93462cecfc7dc9782025-02-03T01:01:07ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/178291178291Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré SyndromeYahia Z. Imam0Dirk Deleu1Department of Neurology (Medicine), Hamad Medical Corporation, P.O. Box 3050, Doha, QatarDepartment of Neurology (Medicine), Hamad Medical Corporation, P.O. Box 3050, Doha, QatarBackground. Guillain-Barré syndrome (GBS) has many variants with distinct presentations. Ptosis as an initial presentation is rare. Case Report. We describe a young female with bilateral ptosis without ophthalmoplegia as the initial presentation of Guillain-Barré ptosis in an anti-GQ1b IgG antibody negative patient with a favorable outcome to intravenous immunoglobulins. Objectives. Our paper highlights the importance of recognizing GBS as a potential etiology in a patient presenting with isolated ptosis, particularly since the course of GBS can be more dramatic than in the anti-GBQ1b syndromes such as ophthalmoparesis without ataxia and Miller Fisher syndrome or ocular myasthenia. Conclusion. This is the first paper of anti-GBQ1b antibody negative GBS presenting with isolated ptosis without ophthalmoparesis. GBS should be included in the list of differential diagnosis of such presentations.http://dx.doi.org/10.1155/2013/178291
spellingShingle Yahia Z. Imam
Dirk Deleu
Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré Syndrome
Case Reports in Neurological Medicine
title Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré Syndrome
title_full Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré Syndrome
title_fullStr Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré Syndrome
title_full_unstemmed Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré Syndrome
title_short Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré Syndrome
title_sort isolated bilateral ptosis as an early sign of guillain barre syndrome
url http://dx.doi.org/10.1155/2013/178291
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