Exposure to violence and risk of hypertensive disorders in pregnancy: Systematic review and meta-analysis

Background: Hypertensive disorders during pregnancy (HDP) are a significant global health concern, affecting 5–10 % of pregnancies and contributing to maternal and newborn morbidity and mortality. While various factors, including genetics and physiological changes, influence the development of HDP,...

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Main Authors: Prakasini Satapathy, Abhay M. Gaidhane, Nasir Vadia, Soumya V. Menon, Kattela Chennakesavulu, Rajashree Panigrahi, Ganesh Bushi, Mahendra Singh, Sanjit Sah, Awakash Turkar, S. Govinda Rao, Khang Wen Goh, Muhammed Shabil, Edward Mawejje
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:European Journal of Obstetrics & Gynecology and Reproductive Biology: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590161325000341
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author Prakasini Satapathy
Abhay M. Gaidhane
Nasir Vadia
Soumya V. Menon
Kattela Chennakesavulu
Rajashree Panigrahi
Ganesh Bushi
Mahendra Singh
Sanjit Sah
Awakash Turkar
S. Govinda Rao
Khang Wen Goh
Muhammed Shabil
Edward Mawejje
author_facet Prakasini Satapathy
Abhay M. Gaidhane
Nasir Vadia
Soumya V. Menon
Kattela Chennakesavulu
Rajashree Panigrahi
Ganesh Bushi
Mahendra Singh
Sanjit Sah
Awakash Turkar
S. Govinda Rao
Khang Wen Goh
Muhammed Shabil
Edward Mawejje
author_sort Prakasini Satapathy
collection DOAJ
description Background: Hypertensive disorders during pregnancy (HDP) are a significant global health concern, affecting 5–10 % of pregnancies and contributing to maternal and newborn morbidity and mortality. While various factors, including genetics and physiological changes, influence the development of HDP, emerging evidence suggests a strong association with psychosocial stressors, particularly exposure to violence. This meta-analysis aimed to assess the association between exposure to violence and risk of hypertensive disorders in pregnancy. Methods: A literature review was performed across EMBASE, PubMed, and Web of Science from their inception until October 2024. The review included observational studies that examined exposure to various type of violence and their association with hypertensive disorders in pregnancy. Pooled effect estimates, including odds ratios (ORs) and relative risks (RRs) were computed using a random-effects model. Results: Sixteen studies met the inclusion criteria. Meta-analysis revealed that violence exposure during pregnancy was associated with a significantly increased risk of HDP, with a pooled OR of 1.380 (95 % CI: 1.079–1.765) and a pooled RR of 1.235 (95 % CI: 1.074–1.420). Subgroup analysis indicated that cohort studies demonstrated a stronger association (OR: 1.726, 95 % CI: 1.182–2.519) compared to cross-sectional studies (OR: 1.112, 95 % CI: 1.009–1.226). Conclusion: Experiencing violence during pregnancy is significantly linked to a heightened risk of HDP, indicating the need for regular violence screening and early preventive measures in prenatal care. Public health initiatives focused on reducing violence against women, especially during pregnancy, are crucial for improving maternal health and lowering the incidence of hypertensive complications.
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spelling doaj-art-dbec979d91a64ef48a30c4b15af3342c2025-08-20T03:20:01ZengElsevierEuropean Journal of Obstetrics & Gynecology and Reproductive Biology: X2590-16132025-06-012610039810.1016/j.eurox.2025.100398Exposure to violence and risk of hypertensive disorders in pregnancy: Systematic review and meta-analysisPrakasini Satapathy0Abhay M. Gaidhane1Nasir Vadia2Soumya V. Menon3Kattela Chennakesavulu4Rajashree Panigrahi5Ganesh Bushi6Mahendra Singh7Sanjit Sah8Awakash Turkar9S. Govinda Rao10Khang Wen Goh11Muhammed Shabil12Edward Mawejje13Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India; Faculty of Data Science and Information Technology, INTI International University, Nilai, MalaysiaJawaharlal Nehru Medical College, and Global Health Academy, School of Epidemiology and Public Health. Datta Meghe Institute of Higher Education, Wardha, IndiaMarwadi University Research Center, Department of Pharmaceutical Sciences, Faculty of Health Sciences, Marwadi University, Rajkot, Gujarat 360003, IndiaDepartment of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, IndiaDepartment of Chemistry, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, IndiaDepartment of Microbiology, IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751003, IndiaSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, IndiaDepartment of Biotechnology, Graphic Era (Deemed to be University), Clement Town, Dehradun 248002, India; Graphic Era Hill University, Clement Town, Dehradun, IndiaDepartment of Paediatrics, Dr. D. Y. Patil Medical College Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University), Pimpri, Pune, Maharashtra 411018, India; Department of Public Health Dentistry, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth (Deemed-to-be-University), Pune, Maharashtra 411018, India; Department of Medicine, Korea Universtiy, Seoul, South KoreaCentre for Research Impact and Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab 140401, India; Division of Research and Innovation, Uttaranchal University, Dehradun, IndiaDepartment of Data Science, Gokaraju Rangaraju Institute of Engineering and Technology, Bachupally, Hyderabad, Telangana 500090, IndiaFaculty of Data Science and Information Technology, INTI International University, Nilai, Malaysia; Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, IndonesiaGlobal Center for Evidence Synthesis, Chandigarh, 160036, India; Medical Laboratories Techniques Department, AL-Mustaqbal University, Hillah, Babil 51001, IraqSchool of Public Health, Makerere University College of Health Sciences, Mulago Hill, Kampala, Uganda; Corresponding author.Background: Hypertensive disorders during pregnancy (HDP) are a significant global health concern, affecting 5–10 % of pregnancies and contributing to maternal and newborn morbidity and mortality. While various factors, including genetics and physiological changes, influence the development of HDP, emerging evidence suggests a strong association with psychosocial stressors, particularly exposure to violence. This meta-analysis aimed to assess the association between exposure to violence and risk of hypertensive disorders in pregnancy. Methods: A literature review was performed across EMBASE, PubMed, and Web of Science from their inception until October 2024. The review included observational studies that examined exposure to various type of violence and their association with hypertensive disorders in pregnancy. Pooled effect estimates, including odds ratios (ORs) and relative risks (RRs) were computed using a random-effects model. Results: Sixteen studies met the inclusion criteria. Meta-analysis revealed that violence exposure during pregnancy was associated with a significantly increased risk of HDP, with a pooled OR of 1.380 (95 % CI: 1.079–1.765) and a pooled RR of 1.235 (95 % CI: 1.074–1.420). Subgroup analysis indicated that cohort studies demonstrated a stronger association (OR: 1.726, 95 % CI: 1.182–2.519) compared to cross-sectional studies (OR: 1.112, 95 % CI: 1.009–1.226). Conclusion: Experiencing violence during pregnancy is significantly linked to a heightened risk of HDP, indicating the need for regular violence screening and early preventive measures in prenatal care. Public health initiatives focused on reducing violence against women, especially during pregnancy, are crucial for improving maternal health and lowering the incidence of hypertensive complications.http://www.sciencedirect.com/science/article/pii/S2590161325000341Hypertensive disorders in pregnancyViolenceIntimate partner violencePreeclampsiaGestational hypertension
spellingShingle Prakasini Satapathy
Abhay M. Gaidhane
Nasir Vadia
Soumya V. Menon
Kattela Chennakesavulu
Rajashree Panigrahi
Ganesh Bushi
Mahendra Singh
Sanjit Sah
Awakash Turkar
S. Govinda Rao
Khang Wen Goh
Muhammed Shabil
Edward Mawejje
Exposure to violence and risk of hypertensive disorders in pregnancy: Systematic review and meta-analysis
European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Hypertensive disorders in pregnancy
Violence
Intimate partner violence
Preeclampsia
Gestational hypertension
title Exposure to violence and risk of hypertensive disorders in pregnancy: Systematic review and meta-analysis
title_full Exposure to violence and risk of hypertensive disorders in pregnancy: Systematic review and meta-analysis
title_fullStr Exposure to violence and risk of hypertensive disorders in pregnancy: Systematic review and meta-analysis
title_full_unstemmed Exposure to violence and risk of hypertensive disorders in pregnancy: Systematic review and meta-analysis
title_short Exposure to violence and risk of hypertensive disorders in pregnancy: Systematic review and meta-analysis
title_sort exposure to violence and risk of hypertensive disorders in pregnancy systematic review and meta analysis
topic Hypertensive disorders in pregnancy
Violence
Intimate partner violence
Preeclampsia
Gestational hypertension
url http://www.sciencedirect.com/science/article/pii/S2590161325000341
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