Peters Plus syndrome: a recognizable clinical entity

Peters plus syndrome is a rare genetic condition wherein multiple systemic involvement with distinctive facial features are manifested, whilst the hallmark is Peters anomaly, occuring from anterior segment dysgenesis. Homozygous variants in the B3GLCT gene were identified to underlie this dis...

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Main Authors: Gizem Ürel Demir, Naz Güleray Lafcı, Özlem Akgün Doğan, Pelin Özlem Şimşek-Kiper, Gülen Eda Utine
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2020-02-01
Series:The Turkish Journal of Pediatrics
Subjects:
Online Access:https://turkjpediatr.org/article/view/422
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author Gizem Ürel Demir
Naz Güleray Lafcı
Özlem Akgün Doğan
Pelin Özlem Şimşek-Kiper
Gülen Eda Utine
author_facet Gizem Ürel Demir
Naz Güleray Lafcı
Özlem Akgün Doğan
Pelin Özlem Şimşek-Kiper
Gülen Eda Utine
author_sort Gizem Ürel Demir
collection DOAJ
description Peters plus syndrome is a rare genetic condition wherein multiple systemic involvement with distinctive facial features are manifested, whilst the hallmark is Peters anomaly, occuring from anterior segment dysgenesis. Homozygous variants in the B3GLCT gene were identified to underlie this disorder. We here report on a onemonth- old female patient with typical features characteristic of Peters plus syndrome in whom a homozygous pathogenic mutation in the B3GLCT gene was detected.
format Article
id doaj-art-dbdc980081ee485c8882beaa82c9e992
institution OA Journals
issn 0041-4301
2791-6421
language English
publishDate 2020-02-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-dbdc980081ee485c8882beaa82c9e9922025-08-20T02:01:47ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212020-02-0162110.24953/turkjped.2020.01.020Peters Plus syndrome: a recognizable clinical entityGizem Ürel Demir0Naz Güleray Lafcı1Özlem Akgün Doğan2Pelin Özlem Şimşek-Kiper3Gülen Eda Utine4Division of Pediatric Genetics, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.Department of Medical Genetics, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Genetics, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Genetics, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Genetics, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. Peters plus syndrome is a rare genetic condition wherein multiple systemic involvement with distinctive facial features are manifested, whilst the hallmark is Peters anomaly, occuring from anterior segment dysgenesis. Homozygous variants in the B3GLCT gene were identified to underlie this disorder. We here report on a onemonth- old female patient with typical features characteristic of Peters plus syndrome in whom a homozygous pathogenic mutation in the B3GLCT gene was detected. https://turkjpediatr.org/article/view/422B3GLCTPeters anomalyPeters plus syndrome
spellingShingle Gizem Ürel Demir
Naz Güleray Lafcı
Özlem Akgün Doğan
Pelin Özlem Şimşek-Kiper
Gülen Eda Utine
Peters Plus syndrome: a recognizable clinical entity
The Turkish Journal of Pediatrics
B3GLCT
Peters anomaly
Peters plus syndrome
title Peters Plus syndrome: a recognizable clinical entity
title_full Peters Plus syndrome: a recognizable clinical entity
title_fullStr Peters Plus syndrome: a recognizable clinical entity
title_full_unstemmed Peters Plus syndrome: a recognizable clinical entity
title_short Peters Plus syndrome: a recognizable clinical entity
title_sort peters plus syndrome a recognizable clinical entity
topic B3GLCT
Peters anomaly
Peters plus syndrome
url https://turkjpediatr.org/article/view/422
work_keys_str_mv AT gizemureldemir petersplussyndromearecognizableclinicalentity
AT nazguleraylafcı petersplussyndromearecognizableclinicalentity
AT ozlemakgundogan petersplussyndromearecognizableclinicalentity
AT pelinozlemsimsekkiper petersplussyndromearecognizableclinicalentity
AT gulenedautine petersplussyndromearecognizableclinicalentity