Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging

Aging is a complex journey shaped by interactions among mechanisms, biochemistry, physiology, and social habits. This review explores aging's core facets by uncovering the mechanisms driving cellular senescence, oxidative stress, telomere shortening, and mitochondrial dysfunction.The review als...

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Main Authors: Folake Olubukola Asejeje, Olalekan Bukunmi Ogunro
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Archives of Gerontology and Geriatrics Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950307823000036
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author Folake Olubukola Asejeje
Olalekan Bukunmi Ogunro
author_facet Folake Olubukola Asejeje
Olalekan Bukunmi Ogunro
author_sort Folake Olubukola Asejeje
collection DOAJ
description Aging is a complex journey shaped by interactions among mechanisms, biochemistry, physiology, and social habits. This review explores aging's core facets by uncovering the mechanisms driving cellular senescence, oxidative stress, telomere shortening, and mitochondrial dysfunction.The review also delves into the biochemistry and physiology of aging, shedding light on hormonal shifts, genetic influences, and immune system modifications that contribute to the aging process. It navigates the terrain of social habits linked to aging, considering the profound impact of dietary choices, physical activity, social engagement, and stress management.These elements intricately intertwine, emphasizing the holistic nature of aging. The complex interplay between mechanisms, biochemistry, physiology, and social habits underscores the need for a comprehensive understanding of aging that transcends single disciplines.Deciphering these factors underscores the significance of personalized approaches to healthy aging. Tailoring interventions to individual genetics, lifestyles, and health needs emerges as a critical strategy for optimizing well-being in later life.In conclusion, this review illuminates the multifaceted nature of aging, urging the embrace of complexity and interdependence. By fostering a holistic, personalized approach, individuals can navigate the aging journey with grace, vitality, and resilience.
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spelling doaj-art-dbd1416d6f8847b498ff39b5e2d4498c2025-08-20T02:02:57ZengElsevierArchives of Gerontology and Geriatrics Plus2950-30782024-03-011110000310.1016/j.aggp.2023.100003Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of agingFolake Olubukola Asejeje0Olalekan Bukunmi Ogunro1Department of Chemical Sciences, Ajayi Crowther University, Ibadan. NigeriaReproductive & Endocrinology, Toxicology, and Bioinformatics Research Laboratory, Department of Biological Sciences, KolaDaisi University, Ibadan. Nigeria; Corresponding author: Reproductive & Endocrinology, Toxicology, and Bioinformatics Research Laboratory, Department of Biological Sciences, KolaDaisi University, Ibadan. Nigeria, Mobile phone: +2348069845995;Aging is a complex journey shaped by interactions among mechanisms, biochemistry, physiology, and social habits. This review explores aging's core facets by uncovering the mechanisms driving cellular senescence, oxidative stress, telomere shortening, and mitochondrial dysfunction.The review also delves into the biochemistry and physiology of aging, shedding light on hormonal shifts, genetic influences, and immune system modifications that contribute to the aging process. It navigates the terrain of social habits linked to aging, considering the profound impact of dietary choices, physical activity, social engagement, and stress management.These elements intricately intertwine, emphasizing the holistic nature of aging. The complex interplay between mechanisms, biochemistry, physiology, and social habits underscores the need for a comprehensive understanding of aging that transcends single disciplines.Deciphering these factors underscores the significance of personalized approaches to healthy aging. Tailoring interventions to individual genetics, lifestyles, and health needs emerges as a critical strategy for optimizing well-being in later life.In conclusion, this review illuminates the multifaceted nature of aging, urging the embrace of complexity and interdependence. By fostering a holistic, personalized approach, individuals can navigate the aging journey with grace, vitality, and resilience.http://www.sciencedirect.com/science/article/pii/S2950307823000036Aging MechanismsCellular SenescenceBiochemical ChangesSocial HabitsSocial EngagementGenetic Influences
spellingShingle Folake Olubukola Asejeje
Olalekan Bukunmi Ogunro
Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging
Archives of Gerontology and Geriatrics Plus
Aging Mechanisms
Cellular Senescence
Biochemical Changes
Social Habits
Social Engagement
Genetic Influences
title Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging
title_full Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging
title_fullStr Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging
title_full_unstemmed Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging
title_short Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging
title_sort deciphering the mechanisms biochemistry physiology and social habits in the process of aging
topic Aging Mechanisms
Cellular Senescence
Biochemical Changes
Social Habits
Social Engagement
Genetic Influences
url http://www.sciencedirect.com/science/article/pii/S2950307823000036
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