Impact of diabetes and metformin on cuproptosis and ferroptosis in breast cancer patients: an immunohistochemical analysis

Impact of diabetes and metformin on cuproptosis and ferroptosis in breast cancer patients: an immunohistochemical analysis

Abstract Objectives Breast cancer patients with diabetes are often associated with poor prognosis. This study aims to investigate the role of metformin in ferroptosis and cuproptosis in diabetic breast cancer patients and explore its potential impact on clinical outcomes. Methods We retrospectively...

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Bibliographic Details
Main Authors: Changwen Li, Tao Chen, Yuanyuan Li, Chunyan Zhou, Jing Du, Xiaoxin Li, Chuangang Tang, Cheng Ma, Na Deng, Huaixin Cui
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
Breast cancer
Metformin
Cuproptosis
Ferroptosis
Diabetes
Glycolysis
Online Access:https://doi.org/10.1007/s12672-025-02425-2
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