Altered microbiota of the lower respiratory tract and its association with COVID-19 severity analysed by metagenomics and metatranscriptomics

Abstract The interaction between gut and oropharyngeal microbiota plays a significant role in the viral infections like SARS-CoV-2, but role of the lower respiratory tract microbiota remains unclear. Our study utilized metatranscriptomics and metagenomics to analyze the microbial composition of bron...

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Bibliographic Details
Main Authors: Denian Wang, Yishang Duan, Lijuan He, Juan Jiang, Jinghong Xian, Ke Yuan, Rui Zhang, Huohuo Zhang, Jing Wang, Nan Li, Min Huang, Chenggong Hu, Sifeng Lu, Zhiheng Luo, Taibing Deng, Zhongwei Zhang, Bojiang Chen, Weimin Li
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08234-1
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