The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric Ulcer

Double pylorus is an uncommon condition where two communicating channels between the gastric antrum and duodenal bulb exist and found incidentally by esophagogastroduodenoscopy. This case report presented a 77-year old Timorese man with long-term frequent use of nonsteroidal anti-inflammatory drugs...

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Main Authors: Rasco Sandy Sihombing, Taolin Agustinus, Ari Fahrial Syam
Format: Article
Language:English
Published: Interna Publishing 2025-04-01
Series:The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
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Online Access:https://ina-jghe.com/index.php/jghe/article/view/1063
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author Rasco Sandy Sihombing
Taolin Agustinus
Ari Fahrial Syam
author_facet Rasco Sandy Sihombing
Taolin Agustinus
Ari Fahrial Syam
author_sort Rasco Sandy Sihombing
collection DOAJ
description Double pylorus is an uncommon condition where two communicating channels between the gastric antrum and duodenal bulb exist and found incidentally by esophagogastroduodenoscopy. This case report presented a 77-year old Timorese man with long-term frequent use of nonsteroidal anti-inflammatory drugs (NSAIDs) who came to hospital because of hematemesis and melena. The initial endoscopy showed gastric ulcer and the double pylorus. Nine months later, the double pylorus structure fused into one large opening. This elderly patient with a history of NSAIDs abuse was diagnosed with acquired double pylorus due to a gastric ulcer complication. The fusion of the two channels occurred as a result of septum destruction, likely caused by fistulous tract ulceration or mechanical damage from food bolus. This structure predisposes the patient to bile regurgitation and ulcer recurrence, emphasizing the need for continued monitoring and avoidance of ulcerogenic factors. Keywords : double pylorus, gastroduodenal fistula, NSAIDs, gastric ulcer, follow-up
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issn 1411-4801
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publishDate 2025-04-01
publisher Interna Publishing
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series The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
spelling doaj-art-dbc9dbd674f84ce181df1c15578aea862025-08-20T02:25:59ZengInterna PublishingThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy1411-48012302-81812025-04-01261939710.24871/261202593-97923The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric UlcerRasco Sandy Sihombing0Taolin Agustinus1Ari Fahrial Syam2Internal Medicine Division, Mgr Gabriel Manek SVD General Hospital, Atambua, East Nusa TenggaraInternal Medicine Division, Mgr Gabriel Manek SVD General Hospital, Atambua, East Nusa TenggaraDivision of Gastroenterology, Pancreatobiliary and Digestive Endoscopy, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia / Cipto Mangunkusumo General National Hospital, Jakarta, IndonesiaDouble pylorus is an uncommon condition where two communicating channels between the gastric antrum and duodenal bulb exist and found incidentally by esophagogastroduodenoscopy. This case report presented a 77-year old Timorese man with long-term frequent use of nonsteroidal anti-inflammatory drugs (NSAIDs) who came to hospital because of hematemesis and melena. The initial endoscopy showed gastric ulcer and the double pylorus. Nine months later, the double pylorus structure fused into one large opening. This elderly patient with a history of NSAIDs abuse was diagnosed with acquired double pylorus due to a gastric ulcer complication. The fusion of the two channels occurred as a result of septum destruction, likely caused by fistulous tract ulceration or mechanical damage from food bolus. This structure predisposes the patient to bile regurgitation and ulcer recurrence, emphasizing the need for continued monitoring and avoidance of ulcerogenic factors. Keywords : double pylorus, gastroduodenal fistula, NSAIDs, gastric ulcer, follow-uphttps://ina-jghe.com/index.php/jghe/article/view/1063double pylorus, gastroduodenal fistula, nsaids, gastric ulcer, follow-up
spellingShingle Rasco Sandy Sihombing
Taolin Agustinus
Ari Fahrial Syam
The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric Ulcer
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
double pylorus, gastroduodenal fistula, nsaids, gastric ulcer, follow-up
title The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric Ulcer
title_full The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric Ulcer
title_fullStr The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric Ulcer
title_full_unstemmed The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric Ulcer
title_short The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric Ulcer
title_sort evolution of double pylorus associated with nsaids induced gastric ulcer
topic double pylorus, gastroduodenal fistula, nsaids, gastric ulcer, follow-up
url https://ina-jghe.com/index.php/jghe/article/view/1063
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