Linear and Non-Linear Methods to Discriminate Cortical Parcels Based on Neurodynamics: Insights from sEEG Recordings

Understanding human cortical neurodynamics is increasingly important, as highlighted by the European Innovation Council, which prioritises tools for measuring and stimulating brain activity. Unravelling how cytoarchitecture, morphology, and connectivity shape neurodynamics is essential for developin...

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Main Authors: Karolina Armonaite, Livio Conti, Luigi Laura, Michele Primavera, Franca Tecchio
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Fractal and Fractional
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Online Access:https://www.mdpi.com/2504-3110/9/5/278
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author Karolina Armonaite
Livio Conti
Luigi Laura
Michele Primavera
Franca Tecchio
author_facet Karolina Armonaite
Livio Conti
Luigi Laura
Michele Primavera
Franca Tecchio
author_sort Karolina Armonaite
collection DOAJ
description Understanding human cortical neurodynamics is increasingly important, as highlighted by the European Innovation Council, which prioritises tools for measuring and stimulating brain activity. Unravelling how cytoarchitecture, morphology, and connectivity shape neurodynamics is essential for developing technologies that target specific brain regions. Given the dynamic and non-stationary nature of neural interactions, there is an urgent need for non-linear signal analysis methods, in addition to the linear ones, to track local neurodynamics and differentiate cortical parcels. Here, we explore linear and non-linear methods using data from a public stereotactic intracranial EEG (sEEG) dataset, focusing on the superior temporal gyrus (STG), postcentral gyrus (postCG), and precentral gyrus (preCG) in 55 subjects during resting-state wakefulness. For this study, we used a linear Power Spectral Density (PSD) estimate and three non-linear measures: the Higuchi fractal dimension (HFD), a one-dimensional convolutional neural network (1D-CNN), and a one-shot learning model. The PSD was able to distinguish the regions in α, β, and γ frequency bands. The HFD showed a tendency of a higher value in the preCG than in the postCG, and both were higher in the STG. The 1D-CNN showed promise in identifying cortical parcels, with an 85% accuracy for the training set, although performance in the test phase indicates that further refinement is needed to integrate dynamic neural electrical activity patterns into neural networks for suitable classification.
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spelling doaj-art-dbbb1343ec764e6298bc3318c9cfa7612025-08-20T03:14:39ZengMDPI AGFractal and Fractional2504-31102025-04-019527810.3390/fractalfract9050278Linear and Non-Linear Methods to Discriminate Cortical Parcels Based on Neurodynamics: Insights from sEEG RecordingsKarolina Armonaite0Livio Conti1Luigi Laura2Michele Primavera3Franca Tecchio4Faculty of Engineering, Uninettuno University, 00186 Rome, ItalyFaculty of Engineering, Uninettuno University, 00186 Rome, ItalyFaculty of Engineering, Uninettuno University, 00186 Rome, ItalyFaculty of Engineering, Uninettuno University, 00186 Rome, ItalyLaboratory of Electrophysiology for Translational Neuroscience, Institute of Cognitive Sciences and Technologies, Consiglio Nazionale delle Ricerche, 00185 Rome, ItalyUnderstanding human cortical neurodynamics is increasingly important, as highlighted by the European Innovation Council, which prioritises tools for measuring and stimulating brain activity. Unravelling how cytoarchitecture, morphology, and connectivity shape neurodynamics is essential for developing technologies that target specific brain regions. Given the dynamic and non-stationary nature of neural interactions, there is an urgent need for non-linear signal analysis methods, in addition to the linear ones, to track local neurodynamics and differentiate cortical parcels. Here, we explore linear and non-linear methods using data from a public stereotactic intracranial EEG (sEEG) dataset, focusing on the superior temporal gyrus (STG), postcentral gyrus (postCG), and precentral gyrus (preCG) in 55 subjects during resting-state wakefulness. For this study, we used a linear Power Spectral Density (PSD) estimate and three non-linear measures: the Higuchi fractal dimension (HFD), a one-dimensional convolutional neural network (1D-CNN), and a one-shot learning model. The PSD was able to distinguish the regions in α, β, and γ frequency bands. The HFD showed a tendency of a higher value in the preCG than in the postCG, and both were higher in the STG. The 1D-CNN showed promise in identifying cortical parcels, with an 85% accuracy for the training set, although performance in the test phase indicates that further refinement is needed to integrate dynamic neural electrical activity patterns into neural networks for suitable classification.https://www.mdpi.com/2504-3110/9/5/278neurodynamicscortical parcellingsEEGdeep learning
spellingShingle Karolina Armonaite
Livio Conti
Luigi Laura
Michele Primavera
Franca Tecchio
Linear and Non-Linear Methods to Discriminate Cortical Parcels Based on Neurodynamics: Insights from sEEG Recordings
Fractal and Fractional
neurodynamics
cortical parcelling
sEEG
deep learning
title Linear and Non-Linear Methods to Discriminate Cortical Parcels Based on Neurodynamics: Insights from sEEG Recordings
title_full Linear and Non-Linear Methods to Discriminate Cortical Parcels Based on Neurodynamics: Insights from sEEG Recordings
title_fullStr Linear and Non-Linear Methods to Discriminate Cortical Parcels Based on Neurodynamics: Insights from sEEG Recordings
title_full_unstemmed Linear and Non-Linear Methods to Discriminate Cortical Parcels Based on Neurodynamics: Insights from sEEG Recordings
title_short Linear and Non-Linear Methods to Discriminate Cortical Parcels Based on Neurodynamics: Insights from sEEG Recordings
title_sort linear and non linear methods to discriminate cortical parcels based on neurodynamics insights from seeg recordings
topic neurodynamics
cortical parcelling
sEEG
deep learning
url https://www.mdpi.com/2504-3110/9/5/278
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AT luigilaura linearandnonlinearmethodstodiscriminatecorticalparcelsbasedonneurodynamicsinsightsfromseegrecordings
AT micheleprimavera linearandnonlinearmethodstodiscriminatecorticalparcelsbasedonneurodynamicsinsightsfromseegrecordings
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