Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients

Introduction Data on cardiovascular risk and vascular age in patients with human immunodeficiency virus (HIV) from developing countries are scarce. Therefore, the current study aimed to determine the prevalence of cardiovascular risk factors, global cardiovascular risk, and vascular age in a Peruvia...

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Main Authors: German Valenzuela-Rodriguez, Jaime A. Collins, Raul Castillo, Luis R. Illescas, Adrian V. Hernandez, Carlos Diaz-Arocutipa
Format: Article
Language:English
Published: Termedia Publishing House 2024-11-01
Series:HIV & AIDS Review. International Journal of HIV-Related Problems
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Online Access:https://hivaids.termedia.pl/Cardiovascular-risk-factors-global-cardiovascular-risk-and-vascular-age-in-a-cohort,171612,0,2.html
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author German Valenzuela-Rodriguez
Jaime A. Collins
Raul Castillo
Luis R. Illescas
Adrian V. Hernandez
Carlos Diaz-Arocutipa
author_facet German Valenzuela-Rodriguez
Jaime A. Collins
Raul Castillo
Luis R. Illescas
Adrian V. Hernandez
Carlos Diaz-Arocutipa
author_sort German Valenzuela-Rodriguez
collection DOAJ
description Introduction Data on cardiovascular risk and vascular age in patients with human immunodeficiency virus (HIV) from developing countries are scarce. Therefore, the current study aimed to determine the prevalence of cardiovascular risk factors, global cardiovascular risk, and vascular age in a Peruvian cohort of patients with HIV. Material and methods A cross-sectional study was conducted among HIV outpatients between August and December 2018. Global cardiovascular risk was calculated using Framingham risk score and ACC/AHA ASCVD score, and vascular age was evaluated using Framingham adaptation. Results In total, 310 patients were included. The mean age was 47.4 ± 12.8 years, 79.7% were males, and vascular age was 51.2 ± 17.2 years. The most frequent cardiovascular risk factors were dyslipidemia (69%), hypertension (28.7%), and obesity (18.4%). The median Framingham risk score was 6.15 (range, 3-13) points, and was distributed into low- (67.7%), intermediate- (17.5%), and high- (14.8%) risk. The median ASCVD score was 4.85 (range, 2.4-8) points, and was divided into low- (76.2%), moderate- (13.5%), and high- (10.3%) risk. The prevalence of cardiovascular risk factors was higher in the sub-population aged older than 50 years. Conclusions The prevalence of cardiovascular risk factors was high in our cohort of Peruvian patients with HIV. Consequently, overall cardiovascular risk was elevated in > 10% of cases. Vascular age was higher than chronological age.
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series HIV & AIDS Review. International Journal of HIV-Related Problems
spelling doaj-art-dbb938bee1e14d379b84b3e9400327882025-01-27T11:06:39ZengTermedia Publishing HouseHIV & AIDS Review. International Journal of HIV-Related Problems1730-12701732-27072024-11-0123430831310.5114/hivar/171612171612Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patientsGerman Valenzuela-Rodriguez0https://orcid.org/0000-0002-8595-9549Jaime A. Collins1https://orcid.org/0000-0002-4168-3157Raul Castillo2https://orcid.org/0000-0001-6316-3331Luis R. Illescas3https://orcid.org/0000-0001-9050-0241Adrian V. Hernandez4https://orcid.org/0000-0002-9999-4003Carlos Diaz-Arocutipa5https://orcid.org/0000-0002-5101-2832Systematic Reviews and Meta-analysis Unit (URSIGET), San Ignacio de Loyola University, Lima, PeruInfectious Diseases Service, Department of Internal Medicine, Almenara General Hospital, EsSalud, Lima, PeruInfectious Diseases Service, Department of Internal Medicine, Almenara General Hospital, EsSalud, Lima, PeruInfectious Diseases Service, Department of Internal Medicine, Almenara General Hospital, EsSalud, Lima, PeruSystematic Reviews and Meta-analysis Unit (URSIGET), San Ignacio de Loyola University, Lima, PeruSystematic Reviews and Meta-analysis Unit (URSIGET), San Ignacio de Loyola University, Lima, PeruIntroduction Data on cardiovascular risk and vascular age in patients with human immunodeficiency virus (HIV) from developing countries are scarce. Therefore, the current study aimed to determine the prevalence of cardiovascular risk factors, global cardiovascular risk, and vascular age in a Peruvian cohort of patients with HIV. Material and methods A cross-sectional study was conducted among HIV outpatients between August and December 2018. Global cardiovascular risk was calculated using Framingham risk score and ACC/AHA ASCVD score, and vascular age was evaluated using Framingham adaptation. Results In total, 310 patients were included. The mean age was 47.4 ± 12.8 years, 79.7% were males, and vascular age was 51.2 ± 17.2 years. The most frequent cardiovascular risk factors were dyslipidemia (69%), hypertension (28.7%), and obesity (18.4%). The median Framingham risk score was 6.15 (range, 3-13) points, and was distributed into low- (67.7%), intermediate- (17.5%), and high- (14.8%) risk. The median ASCVD score was 4.85 (range, 2.4-8) points, and was divided into low- (76.2%), moderate- (13.5%), and high- (10.3%) risk. The prevalence of cardiovascular risk factors was higher in the sub-population aged older than 50 years. Conclusions The prevalence of cardiovascular risk factors was high in our cohort of Peruvian patients with HIV. Consequently, overall cardiovascular risk was elevated in > 10% of cases. Vascular age was higher than chronological age.https://hivaids.termedia.pl/Cardiovascular-risk-factors-global-cardiovascular-risk-and-vascular-age-in-a-cohort,171612,0,2.htmlcardiovascular riskhuman immunodeficiency virusvascular age
spellingShingle German Valenzuela-Rodriguez
Jaime A. Collins
Raul Castillo
Luis R. Illescas
Adrian V. Hernandez
Carlos Diaz-Arocutipa
Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients
HIV & AIDS Review. International Journal of HIV-Related Problems
cardiovascular risk
human immunodeficiency virus
vascular age
title Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients
title_full Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients
title_fullStr Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients
title_full_unstemmed Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients
title_short Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients
title_sort cardiovascular risk factors global cardiovascular risk and vascular age in a cohort of peruvian hiv patients
topic cardiovascular risk
human immunodeficiency virus
vascular age
url https://hivaids.termedia.pl/Cardiovascular-risk-factors-global-cardiovascular-risk-and-vascular-age-in-a-cohort,171612,0,2.html
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