Risk factor analysis of arrhythmia, aortic, and tricuspid regurgitation in children with ventricular septal defect following transcatheter closure

Background. Ventricular septal defect (VSD) is a prevalent congenital heart disease in children, occurring at a rate of 5.27 per 1000 live births. Transcatheter VSD closure is a potentially effective alternative to surgery, considering its less invasive nature, but may cause arrhythmia, aortic and t...

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Main Authors: Alif Mutahhar, Mahrus A. Rahman
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2025-06-01
Series:Zdorovʹe Rebenka
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Online Access:https://childshealth.zaslavsky.com.ua/index.php/journal/article/view/1853
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author Alif Mutahhar
Mahrus A. Rahman
author_facet Alif Mutahhar
Mahrus A. Rahman
author_sort Alif Mutahhar
collection DOAJ
description Background. Ventricular septal defect (VSD) is a prevalent congenital heart disease in children, occurring at a rate of 5.27 per 1000 live births. Transcatheter VSD closure is a potentially effective alternative to surgery, considering its less invasive nature, but may cause arrhythmia, aortic and tricuspid regurgitation as possible complications. This study aims to determine the prevalence and the risk factors for arrhythmia, aortic, and tricuspid regurgitation following transcatheter VSD closure. Materials and methods. A cross-sectional study was conducted at the Dr. Soetomo Hospital from January 2017 to November 2024 in children with VSD following transcatheter closure. Bivariate analysis was done to determine the potential risk factors using Statistical Package for the Social Sciences software version 22.0. Results. The study involved 45 participants, mainly with normal nutritional status. The most common types of VSD were perimembranous and moderate-sized. Most participants didn’t have a history of pulmonary hypertension or heart failure. Post-procedure complications were arrhythmia (17.8 %), tricuspid regurgitation (13.3 %), and aortic regurgitation (11.1 %). No significant factors were found to increase the risk of complications following the intervention. Conclusions. Arrhythmia is the most common complication after VSD transcatheter closure, not influenced by socio-demographic and clinical characteristics as potential risk factors. Monitoring and follow-up care are crucial to identify any potential issues early, allowing for timely intervention.
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institution Kabale University
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spelling doaj-art-dbb2629f363b433fb59705c457ab62d32025-08-20T03:56:42ZengZaslavsky O.Yu.Zdorovʹe Rebenka2224-05512307-11682025-06-0120429630310.22141/2224-0551.20.4.2025.18531853Risk factor analysis of arrhythmia, aortic, and tricuspid regurgitation in children with ventricular septal defect following transcatheter closureAlif Mutahhar0https://orcid.org/0009-0004-4831-3898Mahrus A. Rahman1https://orcid.org/0000-0001-5129-457XFaculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaFaculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaBackground. Ventricular septal defect (VSD) is a prevalent congenital heart disease in children, occurring at a rate of 5.27 per 1000 live births. Transcatheter VSD closure is a potentially effective alternative to surgery, considering its less invasive nature, but may cause arrhythmia, aortic and tricuspid regurgitation as possible complications. This study aims to determine the prevalence and the risk factors for arrhythmia, aortic, and tricuspid regurgitation following transcatheter VSD closure. Materials and methods. A cross-sectional study was conducted at the Dr. Soetomo Hospital from January 2017 to November 2024 in children with VSD following transcatheter closure. Bivariate analysis was done to determine the potential risk factors using Statistical Package for the Social Sciences software version 22.0. Results. The study involved 45 participants, mainly with normal nutritional status. The most common types of VSD were perimembranous and moderate-sized. Most participants didn’t have a history of pulmonary hypertension or heart failure. Post-procedure complications were arrhythmia (17.8 %), tricuspid regurgitation (13.3 %), and aortic regurgitation (11.1 %). No significant factors were found to increase the risk of complications following the intervention. Conclusions. Arrhythmia is the most common complication after VSD transcatheter closure, not influenced by socio-demographic and clinical characteristics as potential risk factors. Monitoring and follow-up care are crucial to identify any potential issues early, allowing for timely intervention.https://childshealth.zaslavsky.com.ua/index.php/journal/article/view/1853arrhythmiaventricular septal defecttranscatheter closureaortic regurgitationtricuspid regurgitation
spellingShingle Alif Mutahhar
Mahrus A. Rahman
Risk factor analysis of arrhythmia, aortic, and tricuspid regurgitation in children with ventricular septal defect following transcatheter closure
Zdorovʹe Rebenka
arrhythmia
ventricular septal defect
transcatheter closure
aortic regurgitation
tricuspid regurgitation
title Risk factor analysis of arrhythmia, aortic, and tricuspid regurgitation in children with ventricular septal defect following transcatheter closure
title_full Risk factor analysis of arrhythmia, aortic, and tricuspid regurgitation in children with ventricular septal defect following transcatheter closure
title_fullStr Risk factor analysis of arrhythmia, aortic, and tricuspid regurgitation in children with ventricular septal defect following transcatheter closure
title_full_unstemmed Risk factor analysis of arrhythmia, aortic, and tricuspid regurgitation in children with ventricular septal defect following transcatheter closure
title_short Risk factor analysis of arrhythmia, aortic, and tricuspid regurgitation in children with ventricular septal defect following transcatheter closure
title_sort risk factor analysis of arrhythmia aortic and tricuspid regurgitation in children with ventricular septal defect following transcatheter closure
topic arrhythmia
ventricular septal defect
transcatheter closure
aortic regurgitation
tricuspid regurgitation
url https://childshealth.zaslavsky.com.ua/index.php/journal/article/view/1853
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