Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis
Non-steroid anti-inflammatory drugs (NSAID) were and still remain the main means for arresting acute and controlling chronic pains in therapeutic practice. However, serious complications that may be caused by these drugs essentially limit their application. Therapists need distinct and reasonable gu...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2014-03-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/513 |
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| _version_ | 1849303400701755392 |
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| author | Andrey Evgenyevich Karateev |
| author_facet | Andrey Evgenyevich Karateev |
| author_sort | Andrey Evgenyevich Karateev |
| collection | DOAJ |
| description | Non-steroid anti-inflammatory drugs (NSAID) were and still remain the main means for arresting acute and controlling chronic pains in therapeutic practice. However, serious complications that may be caused by these drugs essentially limit their application. Therapists need distinct and reasonable guidelines on NSAID prescription depending on presence of a comorbid pathology and risk factors associated with the gastrointestinal tract and cardiovascular system. World renowned experts have been actively studying this problem. The main aspects of NSAID efficiency and safety are discussed in this study; the risk factors are ranked according to their significance; and an algorithm of reasonable drug prescription, including prevention of potential complications, is proposed. |
| format | Article |
| id | doaj-art-dbad7e37fedc45eb9203f6d7e87d7551 |
| institution | Kabale University |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2014-03-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-dbad7e37fedc45eb9203f6d7e87d75512025-08-20T03:59:57ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2014-03-0181647210.14412/1996-7012-2014-1-64-721818Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxisAndrey Evgenyevich Karateev0V.A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, Russia; Kashirskoye shosse 34A, Moscow, 115522 RussiaNon-steroid anti-inflammatory drugs (NSAID) were and still remain the main means for arresting acute and controlling chronic pains in therapeutic practice. However, serious complications that may be caused by these drugs essentially limit their application. Therapists need distinct and reasonable guidelines on NSAID prescription depending on presence of a comorbid pathology and risk factors associated with the gastrointestinal tract and cardiovascular system. World renowned experts have been actively studying this problem. The main aspects of NSAID efficiency and safety are discussed in this study; the risk factors are ranked according to their significance; and an algorithm of reasonable drug prescription, including prevention of potential complications, is proposed.https://mrj.ima-press.net/mrj/article/view/513non-steroid anti-inflammatory drugsgastropathycardiovascular complicationsprophylaxiscelecoxibnaproxenproton pump inhibitorslow-dose aspirin |
| spellingShingle | Andrey Evgenyevich Karateev Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis Современная ревматология non-steroid anti-inflammatory drugs gastropathy cardiovascular complications prophylaxis celecoxib naproxen proton pump inhibitors low-dose aspirin |
| title | Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis |
| title_full | Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis |
| title_fullStr | Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis |
| title_full_unstemmed | Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis |
| title_short | Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis |
| title_sort | quantification and qualification of complication risks at use of non steroid anti inflammatory drugs as a basis for recommendations on their use and prophylaxis |
| topic | non-steroid anti-inflammatory drugs gastropathy cardiovascular complications prophylaxis celecoxib naproxen proton pump inhibitors low-dose aspirin |
| url | https://mrj.ima-press.net/mrj/article/view/513 |
| work_keys_str_mv | AT andreyevgenyevichkarateev quantificationandqualificationofcomplicationrisksatuseofnonsteroidantiinflammatorydrugsasabasisforrecommendationsontheiruseandprophylaxis |