Arginine regulates the mucoid phenotype of hypervirulent Klebsiella pneumoniae

Abstract Hypervirulent Klebsiella pneumoniae causes severe community-acquired infections, with its mucoid phenotype resulting from altered capsular polysaccharide chain length. While both environmental and genetic factors influence mucoidy, the cues regulating it remain unclear. Here, we show that c...

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Bibliographic Details
Main Authors: Brooke E. Ryan, Caitlyn L. Holmes, Drew J. Stark, Grace E. Shepard, Emma G. Mills, Saroj Khadka, Daria Van Tyne, Michael A. Bachman, Laura A. Mike
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61047-y
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