Statins and their antiarrhythmic activity
Clinical trials of modern antiarrhythmics often demonstrate their ineffectiveness in life-threatening ventricular arrhythmias and sudden cardiac death (SCD), as well as inadequate pharmacological control in atrial fibrillation (AF). Together with cholesterol-lowering effect, statins demonstrate vari...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
1970-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1610 |
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| Summary: | Clinical trials of modern antiarrhythmics often demonstrate their ineffectiveness in life-threatening ventricular arrhythmias and sudden cardiac death (SCD), as well as inadequate pharmacological control in atrial fibrillation (AF). Together with cholesterol-lowering effect, statins demonstrate various pleiotropic effects (anti-inflammatory, anti-proliferative, endothelial function improvement, etc.). Statins can reduce the risk of life-threatening arrhythmias and SCD in patients with acute myocardial infarction, after coronary revascularization and implantation of cardioverter-defibrillator. Statin therapy may decrease recurrent AF risk. |
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| ISSN: | 1728-8800 2619-0125 |