GS-DTA: integrating graph and sequence models for predicting drug-target binding affinity
Abstract Background Drug-target binding affinity (DTA) prediction is vital in drug discovery and repositioning, more and more researchers are beginning to focus on this. Many effective methods have been proposed. However, some current methods have certain shortcomings in focusing on important nodes...
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Main Authors: | Junwei Luo, Ziguang Zhu, Zhenhan Xu, Chuanle Xiao, Jingjing Wei, Jiquan Shen |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12864-025-11234-4 |
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