Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based study

Objective We evaluated whether placenta accreta spectrum (PAS) patients who delivered at accreta centers had reduced severe maternal morbidity (SMM), and we tested for the presence of racial disparity in SMM at these centers.Methods This is a mixed-methods, cross-sectional, population-based study of...

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Main Authors: Kimberly D. Gregory, Moshe Fridman, Samia Saeb, Naomi Greene, Lisa M. Korst
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:The Journal of Maternal-Fetal & Neonatal Medicine
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Online Access:https://www.tandfonline.com/doi/10.1080/14767058.2025.2515608
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author Kimberly D. Gregory
Moshe Fridman
Samia Saeb
Naomi Greene
Lisa M. Korst
author_facet Kimberly D. Gregory
Moshe Fridman
Samia Saeb
Naomi Greene
Lisa M. Korst
author_sort Kimberly D. Gregory
collection DOAJ
description Objective We evaluated whether placenta accreta spectrum (PAS) patients who delivered at accreta centers had reduced severe maternal morbidity (SMM), and we tested for the presence of racial disparity in SMM at these centers.Methods This is a mixed-methods, cross-sectional, population-based study of California hospitals with at least 200 annual delivery discharges from 2019 to 2021. Hospital discharge data from 2018 were used to assess the distribution of PAS cases in California hospitals and identify “high-volume” accreta hospitals (≥6 PAS cases). Hospitals meeting 7 predefined criteria by interview were labeled as accreta centers. Delivery discharges with PAS diagnostic codes from 2019 to 2021 were aggregated for these hospitals. Bivariate analyses were performed between patient risk factors and “performance” SMM (pSMM) (Yes/No). pSMM is a modified version of the Centers for Disease Control and Prevention SMM measure for hospital comparisons of potentially preventable SMM. We report rates of pSMM (defined without counting hysterectomy) by center status. A multiple hierarchical logistic regression model was constructed for the pSMM outcome. Observed-to-expected (O/E) ratios for pSMM were calculated to evaluate differences by race/ethnicity.Results There were 25 high-volume study hospitals, of which 17 (68%) qualified as accreta centers. Of 1791 PAS cases in California (prevalence of 0.15%), 788 delivered at the 25 hospitals and composed the study population. Centers delivered 93.4% of the percreta cases, 89.6% of increta cases, and 79.5% of the accreta cases, p = .0003. Rates of pSMM were 8.8% (n = 70) overall, (8.4% in centers and 11.0% in non-centers; p = .323). PAS patients were more likely to experience pSMM if they were delivered at non-centers (odds ratio 2.09, 95% confidence interval 0.91–4.80, p = .080). No differences in aggregate O/E ratios by race/ethnicity were identified.Conclusions PAS patients delivered at non-centers were twice as likely to experience pSMM, although this finding did not reach statistical significance. As rates of PAS increase, the development of standardized metrics to track improvement in clinical and patient-reported outcome measures appears warranted.
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spelling doaj-art-db86acc687304cfb9dbdfce85029d94a2025-08-20T02:31:27ZengTaylor & Francis GroupThe Journal of Maternal-Fetal & Neonatal Medicine1476-70581476-49542025-12-0138110.1080/14767058.2025.2515608Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based studyKimberly D. Gregory0Moshe Fridman1Samia Saeb2Naomi Greene3Lisa M. Korst4Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Burns Allen Research Institute, Los Angeles, CA, USAAMF Consulting, Los Angeles, CA, USADepartment of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Burns Allen Research Institute, Los Angeles, CA, USADepartment of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Burns Allen Research Institute, Los Angeles, CA, USAAMF Consulting, Los Angeles, CA, USAObjective We evaluated whether placenta accreta spectrum (PAS) patients who delivered at accreta centers had reduced severe maternal morbidity (SMM), and we tested for the presence of racial disparity in SMM at these centers.Methods This is a mixed-methods, cross-sectional, population-based study of California hospitals with at least 200 annual delivery discharges from 2019 to 2021. Hospital discharge data from 2018 were used to assess the distribution of PAS cases in California hospitals and identify “high-volume” accreta hospitals (≥6 PAS cases). Hospitals meeting 7 predefined criteria by interview were labeled as accreta centers. Delivery discharges with PAS diagnostic codes from 2019 to 2021 were aggregated for these hospitals. Bivariate analyses were performed between patient risk factors and “performance” SMM (pSMM) (Yes/No). pSMM is a modified version of the Centers for Disease Control and Prevention SMM measure for hospital comparisons of potentially preventable SMM. We report rates of pSMM (defined without counting hysterectomy) by center status. A multiple hierarchical logistic regression model was constructed for the pSMM outcome. Observed-to-expected (O/E) ratios for pSMM were calculated to evaluate differences by race/ethnicity.Results There were 25 high-volume study hospitals, of which 17 (68%) qualified as accreta centers. Of 1791 PAS cases in California (prevalence of 0.15%), 788 delivered at the 25 hospitals and composed the study population. Centers delivered 93.4% of the percreta cases, 89.6% of increta cases, and 79.5% of the accreta cases, p = .0003. Rates of pSMM were 8.8% (n = 70) overall, (8.4% in centers and 11.0% in non-centers; p = .323). PAS patients were more likely to experience pSMM if they were delivered at non-centers (odds ratio 2.09, 95% confidence interval 0.91–4.80, p = .080). No differences in aggregate O/E ratios by race/ethnicity were identified.Conclusions PAS patients delivered at non-centers were twice as likely to experience pSMM, although this finding did not reach statistical significance. As rates of PAS increase, the development of standardized metrics to track improvement in clinical and patient-reported outcome measures appears warranted.https://www.tandfonline.com/doi/10.1080/14767058.2025.2515608Placenta accreta spectrumsevere maternal morbidityracial disparitymaternal levels of carecenters of excellence
spellingShingle Kimberly D. Gregory
Moshe Fridman
Samia Saeb
Naomi Greene
Lisa M. Korst
Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based study
The Journal of Maternal-Fetal & Neonatal Medicine
Placenta accreta spectrum
severe maternal morbidity
racial disparity
maternal levels of care
centers of excellence
title Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based study
title_full Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based study
title_fullStr Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based study
title_full_unstemmed Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based study
title_short Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based study
title_sort accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in california a mixed methods population based study
topic Placenta accreta spectrum
severe maternal morbidity
racial disparity
maternal levels of care
centers of excellence
url https://www.tandfonline.com/doi/10.1080/14767058.2025.2515608
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