Multi-functional Ag2O-NiO composite bio-catalyst: Efficacy in breast cancer and anti-microbial properties
Silver and nickel composites are known for enhancing biocatalytic activity and have substantial potential in biomedical engineering due to their comprehensive applications. Here, we synthesized an Ag2O/NiO composite using the microwave hydrothermal method and characterized it by XRD, SEM, DLS, FTIR,...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-07-01
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| Series: | Next Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949822825001431 |
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| Summary: | Silver and nickel composites are known for enhancing biocatalytic activity and have substantial potential in biomedical engineering due to their comprehensive applications. Here, we synthesized an Ag2O/NiO composite using the microwave hydrothermal method and characterized it by XRD, SEM, DLS, FTIR, TEM, and XPS analysis. The Ag2O/NiO composite catalyst was tested against the breast cancer cell line MDA-MB-231 and showed dose-dependent growth inhibition with IC50 values of 100, 250, 500, and 1000 μg/ml−1 as determined by the MTT assay. In addition, the composite showed antimicrobial activity against Escherichia coli (MTCC 7410), Staphylococcus aureus (MTCC 7443), Fusarium oxysporum (RCMB 001004), and Aspergillus niger (RCMB 02724). These results suggest that the Ag2O/NiO composite is an active biocatalyst with promising antimicrobial and anticancer properties. |
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| ISSN: | 2949-8228 |