Overexpression of miR-671-3p alleviates postmenopausal osteoporosis by targeting GREM2 to activate BMP2/SMAD signaling pathway

Overexpression of miR-671-3p alleviates postmenopausal osteoporosis by targeting GREM2 to activate BMP2/SMAD signaling pathway

Abstract Background Increased fracture risk is linked to postmenopausal osteoporosis (PMOP), and elucidating the function of microRNAs (miRNAs) in this condition is vital for identifying individuals at high risk of fractures. This research focused on exploring the function and mechanism of miR-671-3...

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Bibliographic Details
Main Authors: Yanlin Liang, Changqing Gu, Peng Wang, Changwen Gu, Hongwei Ma, Shujun Ren
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Hereditas
Subjects:
PMOP
Osteogenic differentiation
Microgravity
miR-671-3p
GREM2
Online Access:https://doi.org/10.1186/s41065-025-00467-8
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