Distal Placement of an End-to-Side Bypass Graft Anastomosis: A 3D Computational Study

A three-dimensional (3D) computational fluid dynamics study of shear rates around distal end-to-side anastomoses has been conducted. Three 51% and three 75% cross-sectional area-reduced 6 mm cylinders were modeled each with a bypass cylinder attached at a 30-degree angle at different placements dist...

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Main Authors: John Di Cicco, Ayodeji Demuren
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Engineering
Online Access:http://dx.doi.org/10.1155/2013/185823
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author John Di Cicco
Ayodeji Demuren
author_facet John Di Cicco
Ayodeji Demuren
author_sort John Di Cicco
collection DOAJ
description A three-dimensional (3D) computational fluid dynamics study of shear rates around distal end-to-side anastomoses has been conducted. Three 51% and three 75% cross-sectional area-reduced 6 mm cylinders were modeled each with a bypass cylinder attached at a 30-degree angle at different placements distal to the constriction. Steady, incompressible, Newtonian blood flow was assumed, and the full Reynolds-averaged Navier-Stokes equations, turbulent kinetic energy, and specific dissipation rate equations were solved on a locally structured multiblock mesh with hexahedral elements. Consequently, distal placement of an end-to-side bypass graft anastomosis was found to have an influence on the shear rate magnitudes. For the 75% constriction, closer placements produced lower shear rates near the anastomosis. Hence, there is potential for new plaque formation and graft failure.
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spelling doaj-art-db7817a4194d4eeba83f79a51e92540f2025-08-20T02:21:16ZengWileyJournal of Engineering2314-49042314-49122013-01-01201310.1155/2013/185823185823Distal Placement of an End-to-Side Bypass Graft Anastomosis: A 3D Computational StudyJohn Di Cicco0Ayodeji Demuren1Department of Mechanical and Aerospace Engineering, Old Dominion University, Norfolk, VA 23529, USADepartment of Mechanical and Aerospace Engineering, Old Dominion University, Norfolk, VA 23529, USAA three-dimensional (3D) computational fluid dynamics study of shear rates around distal end-to-side anastomoses has been conducted. Three 51% and three 75% cross-sectional area-reduced 6 mm cylinders were modeled each with a bypass cylinder attached at a 30-degree angle at different placements distal to the constriction. Steady, incompressible, Newtonian blood flow was assumed, and the full Reynolds-averaged Navier-Stokes equations, turbulent kinetic energy, and specific dissipation rate equations were solved on a locally structured multiblock mesh with hexahedral elements. Consequently, distal placement of an end-to-side bypass graft anastomosis was found to have an influence on the shear rate magnitudes. For the 75% constriction, closer placements produced lower shear rates near the anastomosis. Hence, there is potential for new plaque formation and graft failure.http://dx.doi.org/10.1155/2013/185823
spellingShingle John Di Cicco
Ayodeji Demuren
Distal Placement of an End-to-Side Bypass Graft Anastomosis: A 3D Computational Study
Journal of Engineering
title Distal Placement of an End-to-Side Bypass Graft Anastomosis: A 3D Computational Study
title_full Distal Placement of an End-to-Side Bypass Graft Anastomosis: A 3D Computational Study
title_fullStr Distal Placement of an End-to-Side Bypass Graft Anastomosis: A 3D Computational Study
title_full_unstemmed Distal Placement of an End-to-Side Bypass Graft Anastomosis: A 3D Computational Study
title_short Distal Placement of an End-to-Side Bypass Graft Anastomosis: A 3D Computational Study
title_sort distal placement of an end to side bypass graft anastomosis a 3d computational study
url http://dx.doi.org/10.1155/2013/185823
work_keys_str_mv AT johndicicco distalplacementofanendtosidebypassgraftanastomosisa3dcomputationalstudy
AT ayodejidemuren distalplacementofanendtosidebypassgraftanastomosisa3dcomputationalstudy