Fabrication of a Spiral Microfluidic Chip for the Mass Production of Lipid Nanoparticles Using Laser Engraving

Fabrication of a Spiral Microfluidic Chip for the Mass Production of Lipid Nanoparticles Using Laser Engraving

A spiral microfluidic chip (SMC) and multi-spiral microfluidic chip (MSMC) for lipid nanoparticle (LNP) production were fabricated using a CO<sub>2</sub> laser engraving method, using perfluoropolyether (PFPE) and poly(ethylene glycol) diacrylate as photopolymerizable base materials. The...

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Bibliographic Details
Main Authors: Inseong Choi, Mincheol Cho, Minseo Song, Byeong Wook Ryu, Bo Mi Kang, Joonyeong Kim, Tae-Kyung Ryu, Sung-Wook Choi
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Micromachines
Subjects:
perfluoropolyether
microfluidics
lipid nanoparticles
mass production
laser engraving
Online Access:https://www.mdpi.com/2072-666X/16/5/501
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