Role of the Barrier Dysfunction of the Intestines in the Development of Alimentary Allergy in Children
Intestinal epithelial barrier plays an important role in prevention of bacterial translocation and food allergens penetration. Article is dedicated to intestinal epithelial barrier disfunctions leading to sensitization. Special attention is paid to molecular mechanisms increasing the allergens penet...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2013-03-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/341 |
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| author | T. E. Borovik S. G. Makarova G. V. Yatsyk T. N. Stepanova S. G. Gribakin |
| author_facet | T. E. Borovik S. G. Makarova G. V. Yatsyk T. N. Stepanova S. G. Gribakin |
| author_sort | T. E. Borovik |
| collection | DOAJ |
| description | Intestinal epithelial barrier plays an important role in prevention of bacterial translocation and food allergens penetration. Article is dedicated to intestinal epithelial barrier disfunctions leading to sensitization. Special attention is paid to molecular mechanisms increasing the allergens penetration through intestinal wall. Phase of sensitization is characterized by antigen-induced crossover IgE connection with FcRI receptor on the surface of mast cell which leads to anaphylactic reaction.Key words: infants, food allergy, sensitization, intestinal epithelial barrier. |
| format | Article |
| id | doaj-art-db6636053ec345898bb760f95d7757ec |
| institution | Kabale University |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2013-03-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-db6636053ec345898bb760f95d7757ec2025-08-20T03:57:26Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352013-03-01122121910.15690/vsp.v12i2.615341Role of the Barrier Dysfunction of the Intestines in the Development of Alimentary Allergy in ChildrenT. E. Borovik0S. G. Makarova1G. V. Yatsyk2T. N. Stepanova3S. G. Gribakin4Scientific Centre of Children Health, RAMS, Moscow; I.M. Sechenov First Moscow State Medical UniversityScientific Centre of Children Health, RAMS, Moscow; I.M. Sechenov First Moscow State Medical UniversityScientific Centre of Children Health, RAMS, MoscowScientific Centre of Children Health, RAMS, MoscowRussian Medical Academy of Postgraduate Education, MoscowIntestinal epithelial barrier plays an important role in prevention of bacterial translocation and food allergens penetration. Article is dedicated to intestinal epithelial barrier disfunctions leading to sensitization. Special attention is paid to molecular mechanisms increasing the allergens penetration through intestinal wall. Phase of sensitization is characterized by antigen-induced crossover IgE connection with FcRI receptor on the surface of mast cell which leads to anaphylactic reaction.Key words: infants, food allergy, sensitization, intestinal epithelial barrier.https://vsp.spr-journal.ru/jour/article/view/341детипищевая аллергиясенсибилизациякишечный эпителиальный барьер |
| spellingShingle | T. E. Borovik S. G. Makarova G. V. Yatsyk T. N. Stepanova S. G. Gribakin Role of the Barrier Dysfunction of the Intestines in the Development of Alimentary Allergy in Children Вопросы современной педиатрии дети пищевая аллергия сенсибилизация кишечный эпителиальный барьер |
| title | Role of the Barrier Dysfunction of the Intestines in the Development of Alimentary Allergy in Children |
| title_full | Role of the Barrier Dysfunction of the Intestines in the Development of Alimentary Allergy in Children |
| title_fullStr | Role of the Barrier Dysfunction of the Intestines in the Development of Alimentary Allergy in Children |
| title_full_unstemmed | Role of the Barrier Dysfunction of the Intestines in the Development of Alimentary Allergy in Children |
| title_short | Role of the Barrier Dysfunction of the Intestines in the Development of Alimentary Allergy in Children |
| title_sort | role of the barrier dysfunction of the intestines in the development of alimentary allergy in children |
| topic | дети пищевая аллергия сенсибилизация кишечный эпителиальный барьер |
| url | https://vsp.spr-journal.ru/jour/article/view/341 |
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