Spines, Plasticity, and Cognition in Alzheimer's Model Mice
The pathological hallmarks of Alzheimer's disease (AD)—widespread synaptic and neuronal loss and the pathological accumulation of amyloid-beta peptide (Aβ) in senile plaques, as well as hyperphosphorylated tau in neurofibrillary tangles—have been known for many decades, but the links between AD...
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Main Authors: | Tara Spires-Jones, Shira Knafo |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2012/319836 |
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