Synthesis of 2D Tungsten disulphide WS2 for biosensing: a unique perspective on emerging applications
Abstract Two-dimensional (2D) materials have garnered momentous consideration owing to their inimitable structural and physiochemical properties, enabling diverse technological applications. Tungsten disulfide (WS2), a prominent transition metal dichalcogenide, exhibits exceptional characteristics s...
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| Format: | Article |
| Language: | English |
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Springer
2025-06-01
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| Series: | Discover Nano |
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| Online Access: | https://doi.org/10.1186/s11671-025-04269-9 |
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| author | Chih-Chiang Wang Arvind Mukundan Riya Karmakar Kadu Samarth Jalindra Hsiang-Chen Wang |
| author_facet | Chih-Chiang Wang Arvind Mukundan Riya Karmakar Kadu Samarth Jalindra Hsiang-Chen Wang |
| author_sort | Chih-Chiang Wang |
| collection | DOAJ |
| description | Abstract Two-dimensional (2D) materials have garnered momentous consideration owing to their inimitable structural and physiochemical properties, enabling diverse technological applications. Tungsten disulfide (WS2), a prominent transition metal dichalcogenide, exhibits exceptional characteristics such as a tunable bandgap, large surface area, and strong biocompatibility, making it highly suitable for biosensing applications. This review explores various WS2 synthesis techniques, including mechanical exfoliation, sonication, and chemical exfoliation, highlighting their impact on nanosheet quality and scalability. Furthermore, it examines WS2’s role in biosensing, particularly in cancer biomarker detection, DNA/RNA sensing, enzyme activity monitoring, and pathogen identification. Despite its promising applications, challenges such as oxidation, long-term stability, and large-scale synthesis persist. Future advancements in hybrid nanostructures, functionalization techniques, and AI-assisted biosensing are expected to enhance WS2’s reliability and expand its practical deployment. By addressing these challenges, WS2-based technologies can drive significant innovations in diagnostics and environmental monitoring. |
| format | Article |
| id | doaj-art-db4f90d5da9d437d84aa8579c7e530a9 |
| institution | DOAJ |
| issn | 2731-9229 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Nano |
| spelling | doaj-art-db4f90d5da9d437d84aa8579c7e530a92025-08-20T03:21:03ZengSpringerDiscover Nano2731-92292025-06-0120112310.1186/s11671-025-04269-9Synthesis of 2D Tungsten disulphide WS2 for biosensing: a unique perspective on emerging applicationsChih-Chiang Wang0Arvind Mukundan1Riya Karmakar2Kadu Samarth Jalindra3Hsiang-Chen Wang4Department of Internal Medicine, Kaohsiung Armed Forces General HospitalDepartment of Mechanical Engineering, National Chung Cheng UniversityDepartment of Mechanical Engineering, National Chung Cheng UniversitySanjivani College of EngineeringDepartment of Mechanical Engineering, National Chung Cheng UniversityAbstract Two-dimensional (2D) materials have garnered momentous consideration owing to their inimitable structural and physiochemical properties, enabling diverse technological applications. Tungsten disulfide (WS2), a prominent transition metal dichalcogenide, exhibits exceptional characteristics such as a tunable bandgap, large surface area, and strong biocompatibility, making it highly suitable for biosensing applications. This review explores various WS2 synthesis techniques, including mechanical exfoliation, sonication, and chemical exfoliation, highlighting their impact on nanosheet quality and scalability. Furthermore, it examines WS2’s role in biosensing, particularly in cancer biomarker detection, DNA/RNA sensing, enzyme activity monitoring, and pathogen identification. Despite its promising applications, challenges such as oxidation, long-term stability, and large-scale synthesis persist. Future advancements in hybrid nanostructures, functionalization techniques, and AI-assisted biosensing are expected to enhance WS2’s reliability and expand its practical deployment. By addressing these challenges, WS2-based technologies can drive significant innovations in diagnostics and environmental monitoring.https://doi.org/10.1186/s11671-025-04269-9Tungsten disulfide (WS2)BiosensingTransition metal dichalcogenides (TMDs)Synthesis methodsHybrid nanostructuresAI-assisted biosensing |
| spellingShingle | Chih-Chiang Wang Arvind Mukundan Riya Karmakar Kadu Samarth Jalindra Hsiang-Chen Wang Synthesis of 2D Tungsten disulphide WS2 for biosensing: a unique perspective on emerging applications Discover Nano Tungsten disulfide (WS2) Biosensing Transition metal dichalcogenides (TMDs) Synthesis methods Hybrid nanostructures AI-assisted biosensing |
| title | Synthesis of 2D Tungsten disulphide WS2 for biosensing: a unique perspective on emerging applications |
| title_full | Synthesis of 2D Tungsten disulphide WS2 for biosensing: a unique perspective on emerging applications |
| title_fullStr | Synthesis of 2D Tungsten disulphide WS2 for biosensing: a unique perspective on emerging applications |
| title_full_unstemmed | Synthesis of 2D Tungsten disulphide WS2 for biosensing: a unique perspective on emerging applications |
| title_short | Synthesis of 2D Tungsten disulphide WS2 for biosensing: a unique perspective on emerging applications |
| title_sort | synthesis of 2d tungsten disulphide ws2 for biosensing a unique perspective on emerging applications |
| topic | Tungsten disulfide (WS2) Biosensing Transition metal dichalcogenides (TMDs) Synthesis methods Hybrid nanostructures AI-assisted biosensing |
| url | https://doi.org/10.1186/s11671-025-04269-9 |
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